Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects

The comparism of the dark adaptation and plasma retinol level (Vitamin A) was a potentially useful method of studying the basic nature of the aging process in vision. The purpose of this study was to determine the effect of age upon the dark adaptation time and plasma retinol level. Dark adaptation...

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Main Authors:	Aung, Nilar, Ohmar, Ohmar, Wai, Nyunt
Format:	Conference or Workshop Item
Language:	English
Published:	2011
Subjects:	QP Physiology
Online Access:	http://irep.iium.edu.my/10712/ http://irep.iium.edu.my/10712/ http://irep.iium.edu.my/10712/1/For_MSPP_Amend_Final_Blue_Health_and_Allied_Sciences.pdf

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recordtype	eprints
spelling	iium-107122012-02-01T02:11:31Z http://irep.iium.edu.my/10712/ Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects Aung, Nilar Ohmar, Ohmar Wai, Nyunt QP Physiology The comparism of the dark adaptation and plasma retinol level (Vitamin A) was a potentially useful method of studying the basic nature of the aging process in vision. The purpose of this study was to determine the effect of age upon the dark adaptation time and plasma retinol level. Dark adaptation time, visual fields and plasma retinol levels were studied in two different age groups of Myanmar subjects (young adults: 18-25 years and middle-aged subjects: 40-60 years) (n=30 each). Dark adaptation time (DAT) was determined by a rapid dark adaptation test adopted from Thornton (1977). Visual field was assessed by manually setting kinetic perimetry. Plasma retinol level was determined by colorimetric method using trifluoroacetic acid (TFA). None of the subjects exhibited subnormal plasma retinol levels. Although the plasma retinol levels of middle-aged subjects were comparable to those of their younger counterparts (66.3 (5.2) µg/dl vs 61.4(8.1) µg/dl) (mean(SD)), the middle-aged subjects had significantly longer DAT (5.7 (1.4) vs 3.6 (1.3) minutes; P<0.05) and significantly greater reduction (P<0.05) in visual fields of both eyes. There was a significant negative correlation (P<0.05) between plasma retinol level and DAT in the middle-aged subjects, but not in young adults. No correlation was found between serum retinol level and visual field reduction in both groups. Even with comparable plasma retinol level, longer DAT and greater reduction of visual field in middle-aged subjects indicated that retinal function might also be affected by the age-related changes in retina. Keywords: Dark Adaptation Time (DAT), Rapid Dark Adaptation Test, Vitamin A, Visual Field, Aging. 2011-05 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/10712/1/For_MSPP_Amend_Final_Blue_Health_and_Allied_Sciences.pdf Aung, Nilar and Ohmar, Ohmar and Wai, Nyunt (2011) Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects. In: 25th Scientific Meeting of The Malaysian Society of Pharmacology & Physiology : Advances In Drug Development For Better Well-Being, 25th -26th May 2011, Serdang, Selangor. (Unpublished) http://medic1.upm.edu.my/MSPP/index.php
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QP Physiology
spellingShingle	QP Physiology Aung, Nilar Ohmar, Ohmar Wai, Nyunt Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
description	The comparism of the dark adaptation and plasma retinol level (Vitamin A) was a potentially useful method of studying the basic nature of the aging process in vision. The purpose of this study was to determine the effect of age upon the dark adaptation time and plasma retinol level. Dark adaptation time, visual fields and plasma retinol levels were studied in two different age groups of Myanmar subjects (young adults: 18-25 years and middle-aged subjects: 40-60 years) (n=30 each). Dark adaptation time (DAT) was determined by a rapid dark adaptation test adopted from Thornton (1977). Visual field was assessed by manually setting kinetic perimetry. Plasma retinol level was determined by colorimetric method using trifluoroacetic acid (TFA). None of the subjects exhibited subnormal plasma retinol levels. Although the plasma retinol levels of middle-aged subjects were comparable to those of their younger counterparts (66.3 (5.2) µg/dl vs 61.4(8.1) µg/dl) (mean(SD)), the middle-aged subjects had significantly longer DAT (5.7 (1.4) vs 3.6 (1.3) minutes; P<0.05) and significantly greater reduction (P<0.05) in visual fields of both eyes. There was a significant negative correlation (P<0.05) between plasma retinol level and DAT in the middle-aged subjects, but not in young adults. No correlation was found between serum retinol level and visual field reduction in both groups. Even with comparable plasma retinol level, longer DAT and greater reduction of visual field in middle-aged subjects indicated that retinal function might also be affected by the age-related changes in retina. Keywords: Dark Adaptation Time (DAT), Rapid Dark Adaptation Test, Vitamin A, Visual Field, Aging.
format	Conference or Workshop Item
author	Aung, Nilar Ohmar, Ohmar Wai, Nyunt
author_facet	Aung, Nilar Ohmar, Ohmar Wai, Nyunt
author_sort	Aung, Nilar
title	Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
title_short	Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
title_full	Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
title_fullStr	Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
title_full_unstemmed	Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
title_sort	some aspects of visual functions and serum retinol levels in young adults and middle aged subjects
publishDate	2011
url	http://irep.iium.edu.my/10712/ http://irep.iium.edu.my/10712/ http://irep.iium.edu.my/10712/1/For_MSPP_Amend_Final_Blue_Health_and_Allied_Sciences.pdf
first_indexed	2023-09-18T20:20:06Z
last_indexed	2023-09-18T20:20:06Z
_version_	1777408049027219456

Some aspects of visual functions and serum retinol levels in young adults and middle aged subjects

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