The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells

The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells

The effects of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin B1 promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0.11-0.17 mM. The effect of cinnamtannin B1 on cellular 2-deoxy-D-[1-3H] glucose uptake in differen...

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Main Authors: Bakhtiar, M. Taher, Abdul Majid, Fadzilah Adibah, Sarmidi, Mohamad Roji
Format: Article
Language:English
Published: Natural Product, Inc. 2007
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/12083/
http://irep.iium.edu.my/12083/
http://irep.iium.edu.my/12083/1/Article-NPC-2-1-61-2007.pdf
id iium-12083
recordtype eprints
spelling iium-120832014-12-09T00:26:45Z http://irep.iium.edu.my/12083/ The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells Bakhtiar, M. Taher Abdul Majid, Fadzilah Adibah Sarmidi, Mohamad Roji RS Pharmacy and materia medica The effects of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin B1 promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0.11-0.17 mM. The effect of cinnamtannin B1 on cellular 2-deoxy-D-[1-3H] glucose uptake in differentiated 3T3-L1 adipocytes, following treatment with a 0.11 mM concentration of cinnamtannin B1 for 15, 30 and 60 minutes, was an increase in the glucose uptake from a basal value to 702.0,1111.0 and 2226.0 cpm, respectively (p<0.005). The comparable glucose uptakes with insulin treatment were 660.0, 1039.0 and 2135.0 cpm, respectively. Wortmannin and cytochalasin B were found to inhibit cinnamtannin B1-stimulated glucose uptake, but sodium orthovanadate increased the glucose uptake. Natural Product, Inc. 2007 Article PeerReviewed application/pdf en http://irep.iium.edu.my/12083/1/Article-NPC-2-1-61-2007.pdf Bakhtiar, M. Taher and Abdul Majid, Fadzilah Adibah and Sarmidi, Mohamad Roji (2007) The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells. Natural Product Communications, 2 (1). pp. 61-66. ISSN 1934-578X http://www.naturalproduct.us.
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Bakhtiar, M. Taher
Abdul Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
description The effects of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin B1 promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0.11-0.17 mM. The effect of cinnamtannin B1 on cellular 2-deoxy-D-[1-3H] glucose uptake in differentiated 3T3-L1 adipocytes, following treatment with a 0.11 mM concentration of cinnamtannin B1 for 15, 30 and 60 minutes, was an increase in the glucose uptake from a basal value to 702.0,1111.0 and 2226.0 cpm, respectively (p<0.005). The comparable glucose uptakes with insulin treatment were 660.0, 1039.0 and 2135.0 cpm, respectively. Wortmannin and cytochalasin B were found to inhibit cinnamtannin B1-stimulated glucose uptake, but sodium orthovanadate increased the glucose uptake.
format Article
author Bakhtiar, M. Taher
Abdul Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
author_facet Bakhtiar, M. Taher
Abdul Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
author_sort Bakhtiar, M. Taher
title The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
title_short The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
title_full The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
title_fullStr The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
title_full_unstemmed The effect of Cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
title_sort effect of cinnamtannin b1 on cell proliferation and glucose uptake of 3t3-l1 cells
publisher Natural Product, Inc.
publishDate 2007
url http://irep.iium.edu.my/12083/
http://irep.iium.edu.my/12083/
http://irep.iium.edu.my/12083/1/Article-NPC-2-1-61-2007.pdf
first_indexed 2023-09-18T20:21:18Z
last_indexed 2023-09-18T20:21:18Z
_version_ 1777408125055270912

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