Antimicrobial compounds from Calophyllum canum

Calophyllum species have been used in traditional medicine for its therapeutic properties in many tropical climate counteries. Calopyllum canum locally known as bintagor merah has been isolated and tested for its antimcirobial activity. Stembarks of C. canum were extracted by soxhlet extraction with...

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Main Authors:	Sheikh, Hasan I, Darnis, Deny Susanti, Bakhtiar, M. Taher, Ahmed, Hanad, Syed Osman Idid, Syed Zahir Idid
Format:	Conference or Workshop Item
Language:	English English
Published:	2010
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/12137/ http://irep.iium.edu.my/12137/1/Icastcover.pdf http://irep.iium.edu.my/12137/2/Icast1.pdf

id	iium-12137
recordtype	eprints
spelling	iium-121372014-12-09T01:35:54Z http://irep.iium.edu.my/12137/ Antimicrobial compounds from Calophyllum canum Sheikh, Hasan I Darnis, Deny Susanti Bakhtiar, M. Taher Ahmed, Hanad Syed Osman Idid, Syed Zahir Idid Q Science (General) Calophyllum species have been used in traditional medicine for its therapeutic properties in many tropical climate counteries. Calopyllum canum locally known as bintagor merah has been isolated and tested for its antimcirobial activity. Stembarks of C. canum were extracted by soxhlet extraction with n-hexane, ethyl acetate and then methanol, successively. The antimictovial activity was carried out by disc difussion method and determination of MIC and MBC values. n-Hexane extracts was active against S.aureus and B.subtili, while methanol extract inhibited the growuth of S.aureus, B.subtilis and E.coli. Ethyl acetate extract was also active against S.aureus and B.subtilis. Both n-haxena and methanol extracts were furhter subjected to column chramotography by guiding of its antimicrobial actvity. Four compounds were sucesfully isolated.; two (D1 and D2) from n-hexane extract and two from methanol (CCM1 and CCM2). The compondsD1 and d2 were active against S.aureus and B. anthracis. While CCM1 and CCM2 were active against S.aureus. Furhter research need to be done to identify the structure of the active compounds and investigate their mood of action. 2010-11-27 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/12137/1/Icastcover.pdf application/pdf en http://irep.iium.edu.my/12137/2/Icast1.pdf Sheikh, Hasan I and Darnis, Deny Susanti and Bakhtiar, M. Taher and Ahmed, Hanad and Syed Osman Idid, Syed Zahir Idid (2010) Antimicrobial compounds from Calophyllum canum. In: International Conference on Advancement in Science and Technology (iCAST2010): The Science of Traditional Practices in Health and Disease, 26-29 Nov 2010, Kuantan, Malaysia.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General)
spellingShingle	Q Science (General) Sheikh, Hasan I Darnis, Deny Susanti Bakhtiar, M. Taher Ahmed, Hanad Syed Osman Idid, Syed Zahir Idid Antimicrobial compounds from Calophyllum canum
description	Calophyllum species have been used in traditional medicine for its therapeutic properties in many tropical climate counteries. Calopyllum canum locally known as bintagor merah has been isolated and tested for its antimcirobial activity. Stembarks of C. canum were extracted by soxhlet extraction with n-hexane, ethyl acetate and then methanol, successively. The antimictovial activity was carried out by disc difussion method and determination of MIC and MBC values. n-Hexane extracts was active against S.aureus and B.subtili, while methanol extract inhibited the growuth of S.aureus, B.subtilis and E.coli. Ethyl acetate extract was also active against S.aureus and B.subtilis. Both n-haxena and methanol extracts were furhter subjected to column chramotography by guiding of its antimicrobial actvity. Four compounds were sucesfully isolated.; two (D1 and D2) from n-hexane extract and two from methanol (CCM1 and CCM2). The compondsD1 and d2 were active against S.aureus and B. anthracis. While CCM1 and CCM2 were active against S.aureus. Furhter research need to be done to identify the structure of the active compounds and investigate their mood of action.
format	Conference or Workshop Item
author	Sheikh, Hasan I Darnis, Deny Susanti Bakhtiar, M. Taher Ahmed, Hanad Syed Osman Idid, Syed Zahir Idid
author_facet	Sheikh, Hasan I Darnis, Deny Susanti Bakhtiar, M. Taher Ahmed, Hanad Syed Osman Idid, Syed Zahir Idid
author_sort	Sheikh, Hasan I
title	Antimicrobial compounds from Calophyllum canum
title_short	Antimicrobial compounds from Calophyllum canum
title_full	Antimicrobial compounds from Calophyllum canum
title_fullStr	Antimicrobial compounds from Calophyllum canum
title_full_unstemmed	Antimicrobial compounds from Calophyllum canum
title_sort	antimicrobial compounds from calophyllum canum
publishDate	2010
url	http://irep.iium.edu.my/12137/ http://irep.iium.edu.my/12137/1/Icastcover.pdf http://irep.iium.edu.my/12137/2/Icast1.pdf
first_indexed	2023-09-18T20:21:23Z
last_indexed	2023-09-18T20:21:23Z
_version_	1777408129754988544

Antimicrobial compounds from Calophyllum canum

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