Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis

Alternanthera sessilis (sessile joyweed) is a herb belongs to the family of Amaranthaceae and widely used as traditional medicine in Malaysia, China, Taiwan, India and Sri Lanka. The use of this plant for antimicrobial purpose is an interesting aspect to be studied. The research was done by bioactiv...

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Main Author:	Bakhtiar, M. Taher
Format:	Monograph
Language:	English
Published:	[s.n.] 2011
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/14138/ http://irep.iium.edu.my/14138/1/RESEARCH_REPORT-IFRG0701-35.pdf

id	iium-14138
recordtype	eprints
spelling	iium-141382014-12-09T01:45:14Z http://irep.iium.edu.my/14138/ Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis Bakhtiar, M. Taher RS Pharmacy and materia medica Alternanthera sessilis (sessile joyweed) is a herb belongs to the family of Amaranthaceae and widely used as traditional medicine in Malaysia, China, Taiwan, India and Sri Lanka. The use of this plant for antimicrobial purpose is an interesting aspect to be studied. The research was done by bioactivity-guided fractionation of the extract on their antimicrobial effects. The antimicrobial activity was performed using disc diffusion method. The antimicrobial activity of the extracts were tested against twelve strain of bacteria such as Enterococcus faecalis, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella dysenteriae, Salmonella paratyphi, Propionibacterium acnes, Staphylococcus epidermidis, Staphylococcus saprophyticus, Bacillus subtilis, Staphylococcus aureus. The ethyl acetate extract of A. sessilies exhibited a moderate activity against S. aureus, S. saprophyticus, E.coli and P.aeruginosa with diameter inhibition of 15, 20, 15 and 15 mm, respectively. In addition of abovementioned sample, ten Malaysian medicinal plants were also examined. Among the sample tested, only Orthosiphon stamineous and Averrhoa belimbi possessed antimicrobial properties. O. stamineus was found to be active against S. saprophyticus and B. subtilis with MIC value of 2.5 and 0.625 mg/mL, respectively. A. belimbi had MIC value of 2.5 mg/mL against S. dysenteriae. [s.n.] 2011 Monograph NonPeerReviewed application/pdf en http://irep.iium.edu.my/14138/1/RESEARCH_REPORT-IFRG0701-35.pdf Bakhtiar, M. Taher (2011) Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis. Project Report. [s.n.]. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Bakhtiar, M. Taher Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
description	Alternanthera sessilis (sessile joyweed) is a herb belongs to the family of Amaranthaceae and widely used as traditional medicine in Malaysia, China, Taiwan, India and Sri Lanka. The use of this plant for antimicrobial purpose is an interesting aspect to be studied. The research was done by bioactivity-guided fractionation of the extract on their antimicrobial effects. The antimicrobial activity was performed using disc diffusion method. The antimicrobial activity of the extracts were tested against twelve strain of bacteria such as Enterococcus faecalis, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella dysenteriae, Salmonella paratyphi, Propionibacterium acnes, Staphylococcus epidermidis, Staphylococcus saprophyticus, Bacillus subtilis, Staphylococcus aureus. The ethyl acetate extract of A. sessilies exhibited a moderate activity against S. aureus, S. saprophyticus, E.coli and P.aeruginosa with diameter inhibition of 15, 20, 15 and 15 mm, respectively. In addition of abovementioned sample, ten Malaysian medicinal plants were also examined. Among the sample tested, only Orthosiphon stamineous and Averrhoa belimbi possessed antimicrobial properties. O. stamineus was found to be active against S. saprophyticus and B. subtilis with MIC value of 2.5 and 0.625 mg/mL, respectively. A. belimbi had MIC value of 2.5 mg/mL against S. dysenteriae.
format	Monograph
author	Bakhtiar, M. Taher
author_facet	Bakhtiar, M. Taher
author_sort	Bakhtiar, M. Taher
title	Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
title_short	Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
title_full	Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
title_fullStr	Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
title_full_unstemmed	Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis
title_sort	bioactivity-guided isolation of antimicrobial agent from alternanthera sessilis
publisher	[s.n.]
publishDate	2011
url	http://irep.iium.edu.my/14138/ http://irep.iium.edu.my/14138/1/RESEARCH_REPORT-IFRG0701-35.pdf
first_indexed	2023-09-18T20:23:18Z
last_indexed	2023-09-18T20:23:18Z
_version_	1777408251017560064

Bioactivity-guided isolation of antimicrobial agent from Alternanthera Sessilis

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