Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan

The effect of iodized and uniodized salt on the concentration of thyroid hormones 2(T3and T4) and thyroid stimulating hormone (TSH) was studied in 411 individuals, who were the residents of Peshawar and its vicinity and were referred by physicians to the radio immunoassay (RIA) laboratory of the Ins...

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Main Authors:	Khan, Alam, Akhter, Shahmim, Siddiqui, M. Mohsin, Nawab, Gul, Khattak, Muzaffar Ali Khan
Format:	Article
Language:	English
Published:	Ansi Network for Scientiific Information 2003
Subjects:	RA0421 Public health. Hygiene. Preventive Medicine
Online Access:	http://irep.iium.edu.my/1654/ http://irep.iium.edu.my/1654/ http://irep.iium.edu.my/1654/1/423-428.pdf

id	iium-1654
recordtype	eprints
spelling	iium-16542013-04-25T01:29:50Z http://irep.iium.edu.my/1654/ Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan Khan, Alam Akhter, Shahmim Siddiqui, M. Mohsin Nawab, Gul Khattak, Muzaffar Ali Khan RA0421 Public health. Hygiene. Preventive Medicine The effect of iodized and uniodized salt on the concentration of thyroid hormones 2(T3and T4) and thyroid stimulating hormone (TSH) was studied in 411 individuals, who were the residents of Peshawar and its vicinity and were referred by physicians to the radio immunoassay (RIA) laboratory of the Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar during 1998 for thyroid hormones tests. Out of these 411 individuals, 148 were using iodized salt and 263 were using uniodized salt. The iodized and uniodized salt users were called experimental and control groups, respectively. Blood samples were taken form both the groups and T3and T4in the blood serum were determined by radio immunoassay (RIA) while TSH was determined by immunoradiometricassay (IRMA). The mean concentration of T3was 2.337 and 2.287 nmol L-1in the experimental and control groups respectively. The mean concentration of T4was 109.415 and 105.918 nmol L-1in the experimental and control groups, respectively. The mean concentration of TSH was 3.99 and 4.55 miu L-1in the experimental and control groups respectively. The result indicated that continuous use of iodized salt increased both T3and T4and decreased TSH in the experimental group which is an indication for thyrotoxicoses. However the increase in T3and decrease in TSH were non significant but the increase in T4was ignificant and at p<0.05 as compared to the control group. The data suggest that long and un-necessary use of iodized salt may produce sub clinical hyperthyroidism and hyrotoxicosis in the plain areas of NWFP. Close monitoring of T3, T4and TSH of individuals, who are using iodized salt, is recommended. Ansi Network for Scientiific Information 2003-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/1654/1/423-428.pdf Khan, Alam and Akhter, Shahmim and Siddiqui, M. Mohsin and Nawab, Gul and Khattak, Muzaffar Ali Khan (2003) Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan. Journal of Medical Sciences, 3 (5-6). pp. 423-428. ISSN 1812-5727 (O), 1682-4474 (P) http://elmericomojica.weebly.com/uploads/1/1/8/3/11833807/journal_of_medical_sciences_2005_5_43-46.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RA0421 Public health. Hygiene. Preventive Medicine
spellingShingle	RA0421 Public health. Hygiene. Preventive Medicine Khan, Alam Akhter, Shahmim Siddiqui, M. Mohsin Nawab, Gul Khattak, Muzaffar Ali Khan Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
description	The effect of iodized and uniodized salt on the concentration of thyroid hormones 2(T3and T4) and thyroid stimulating hormone (TSH) was studied in 411 individuals, who were the residents of Peshawar and its vicinity and were referred by physicians to the radio immunoassay (RIA) laboratory of the Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar during 1998 for thyroid hormones tests. Out of these 411 individuals, 148 were using iodized salt and 263 were using uniodized salt. The iodized and uniodized salt users were called experimental and control groups, respectively. Blood samples were taken form both the groups and T3and T4in the blood serum were determined by radio immunoassay (RIA) while TSH was determined by immunoradiometricassay (IRMA). The mean concentration of T3was 2.337 and 2.287 nmol L-1in the experimental and control groups respectively. The mean concentration of T4was 109.415 and 105.918 nmol L-1in the experimental and control groups, respectively. The mean concentration of TSH was 3.99 and 4.55 miu L-1in the experimental and control groups respectively. The result indicated that continuous use of iodized salt increased both T3and T4and decreased TSH in the experimental group which is an indication for thyrotoxicoses. However the increase in T3and decrease in TSH were non significant but the increase in T4was ignificant and at p<0.05 as compared to the control group. The data suggest that long and un-necessary use of iodized salt may produce sub clinical hyperthyroidism and hyrotoxicosis in the plain areas of NWFP. Close monitoring of T3, T4and TSH of individuals, who are using iodized salt, is recommended.
format	Article
author	Khan, Alam Akhter, Shahmim Siddiqui, M. Mohsin Nawab, Gul Khattak, Muzaffar Ali Khan
author_facet	Khan, Alam Akhter, Shahmim Siddiqui, M. Mohsin Nawab, Gul Khattak, Muzaffar Ali Khan
author_sort	Khan, Alam
title	Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
title_short	Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
title_full	Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
title_fullStr	Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
title_full_unstemmed	Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan
title_sort	continous use of iodized salt may cause thyrotoxicoses in plain areas of north west frontier province (nwfp) of pakistan
publisher	Ansi Network for Scientiific Information
publishDate	2003
url	http://irep.iium.edu.my/1654/ http://irep.iium.edu.my/1654/ http://irep.iium.edu.my/1654/1/423-428.pdf
first_indexed	2023-09-18T20:09:05Z
last_indexed	2023-09-18T20:09:05Z
_version_	1777407355941552128

Continous use of iodized salt may cause thyrotoxicoses in plain areas of North West Frontier Province (NWFP) of Pakistan

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