Some biological activities of Malaysian leech salive extract

Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration...

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Main Authors:	M.Abdualkader, Abdualrahman, Merzouk, Ahmed, Mohammed Ghawi, Abbas, Alaama, Mohammed
Format:	Article
Language:	English
Published:	IIUM Press 2011
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/1/some_biological.pdf

id	iium-16870
recordtype	eprints
spelling	iium-168702012-01-25T10:36:19Z http://irep.iium.edu.my/16870/ Some biological activities of Malaysian leech salive extract M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed R Medicine (General) Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration which increases TT by 100% (IC100) is 43.205 μg/ml plasma. The antimicrobial activity of the saliva was tested against several bacterial spp. (E. coli, P. aeruginosa, B. cereus, Sal. typhi and S. aureus) and fungi spp. (C.albicans and C.neoformans). It was found that saliva has an inhibition activity against Sal. typhi (minimal inhibitory concentration MIC 78.253 μg/ml), S.aureus (MIC 78.253 μg/ml) and E .coli (MIC 121.256 μg/ml). IIUM Press 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/16870/1/some_biological.pdf M.Abdualkader, Abdualrahman and Merzouk, Ahmed and Mohammed Ghawi, Abbas and Alaama, Mohammed (2011) Some biological activities of Malaysian leech salive extract. IIUM Engineering Journal, 12 (4). pp. 1-9. ISSN 1511-788X http://www.iium.edu.my/ejournal/index.php/iiumej/article/view/156/196
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed Some biological activities of Malaysian leech salive extract
description	Leeches were fed on the phagostimulatory solution through parafilm membrane. The satiated leeches were forced to regurgitate the solution by soaking them in an ice-container. The anticoagulant activity was ascertained using thrombin time assay (TT). The result revealed that the saliva concentration which increases TT by 100% (IC100) is 43.205 μg/ml plasma. The antimicrobial activity of the saliva was tested against several bacterial spp. (E. coli, P. aeruginosa, B. cereus, Sal. typhi and S. aureus) and fungi spp. (C.albicans and C.neoformans). It was found that saliva has an inhibition activity against Sal. typhi (minimal inhibitory concentration MIC 78.253 μg/ml), S.aureus (MIC 78.253 μg/ml) and E .coli (MIC 121.256 μg/ml).
format	Article
author	M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed
author_facet	M.Abdualkader, Abdualrahman Merzouk, Ahmed Mohammed Ghawi, Abbas Alaama, Mohammed
author_sort	M.Abdualkader, Abdualrahman
title	Some biological activities of Malaysian leech salive extract
title_short	Some biological activities of Malaysian leech salive extract
title_full	Some biological activities of Malaysian leech salive extract
title_fullStr	Some biological activities of Malaysian leech salive extract
title_full_unstemmed	Some biological activities of Malaysian leech salive extract
title_sort	some biological activities of malaysian leech salive extract
publisher	IIUM Press
publishDate	2011
url	http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/ http://irep.iium.edu.my/16870/1/some_biological.pdf
first_indexed	2023-09-18T20:25:37Z
last_indexed	2023-09-18T20:25:37Z
_version_	1777408396828344320

Some biological activities of Malaysian leech salive extract

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