Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital

We performed a cross-sectional study of the demography, clinical and laboratory features of patients with systemic sclerosis patients followed up in our centre from 1984 to 2007. There were 23 cases with the majority of them (96%) being female. They have a mean age of 50.3 years and a mean disease d...

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Main Authors:	Teh, C. L., Kuan, Yeh Chunn, Wong, J. S.
Format:	Article
Language:	English
Published:	Springer 2009
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/1/Kuan_RheuInt2009_systemic_sclerosis.pdf

id	iium-17285
recordtype	eprints
spelling	iium-172852012-01-27T23:26:17Z http://irep.iium.edu.my/17285/ Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital Teh, C. L. Kuan, Yeh Chunn Wong, J. S. RC Internal medicine We performed a cross-sectional study of the demography, clinical and laboratory features of patients with systemic sclerosis patients followed up in our centre from 1984 to 2007. There were 23 cases with the majority of them (96%) being female. They have a mean age of 50.3 years and a mean disease duration of 6.02 (SD 5.82) years. Our patients comprised of multi-ethnic groups with predominantly Chinese (52%), Sarawak natives (35%) and Malays (13%). They have a mean lag time to diagnosis of 24.8 (SD 34.8) months. All the patients have sclerodermatous skin changes with 16(70%) having diffuse scleroderma and 7(30%) having limited scleroderma. The common clinical manifestations found in our patients were Raynaud’s phenomenon (91%), sclerodactyly (65%), digital ulcers (52%) and pulmonary fibrosis (52%). There was low incidence of pulmonary hypertension (13%) and renal involvement (4%). The majority of our patients (67%) have positive ANA with 33% positive Scl-70. The majority received calcium channel blockers (87%), aspirin (48%) and low-dose prednisolone (48%). One patient developed adenocarcinoma of the lung on follow-up. This study demonstrated the rarity of systemic sclerosis in our centre with considerable lag time to diagnosis in our patients. Diffuse cutaneous systemic scleroderma is more common in our centre with rare pulmonary hypertension and renal involvement. Springer 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/17285/1/Kuan_RheuInt2009_systemic_sclerosis.pdf Teh, C. L. and Kuan, Yeh Chunn and Wong, J. S. (2009) Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital. Rheumatol International, 29 (10). pp. 1243-1245. ISSN ISSN: 0172-8172 (P) ; 1437-160X (O) http://www.springer.com/medicine/rheumatology/journal/296 10.1007/s00296-009-0938-z
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Teh, C. L. Kuan, Yeh Chunn Wong, J. S. Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
description	We performed a cross-sectional study of the demography, clinical and laboratory features of patients with systemic sclerosis patients followed up in our centre from 1984 to 2007. There were 23 cases with the majority of them (96%) being female. They have a mean age of 50.3 years and a mean disease duration of 6.02 (SD 5.82) years. Our patients comprised of multi-ethnic groups with predominantly Chinese (52%), Sarawak natives (35%) and Malays (13%). They have a mean lag time to diagnosis of 24.8 (SD 34.8) months. All the patients have sclerodermatous skin changes with 16(70%) having diffuse scleroderma and 7(30%) having limited scleroderma. The common clinical manifestations found in our patients were Raynaud’s phenomenon (91%), sclerodactyly (65%), digital ulcers (52%) and pulmonary fibrosis (52%). There was low incidence of pulmonary hypertension (13%) and renal involvement (4%). The majority of our patients (67%) have positive ANA with 33% positive Scl-70. The majority received calcium channel blockers (87%), aspirin (48%) and low-dose prednisolone (48%). One patient developed adenocarcinoma of the lung on follow-up. This study demonstrated the rarity of systemic sclerosis in our centre with considerable lag time to diagnosis in our patients. Diffuse cutaneous systemic scleroderma is more common in our centre with rare pulmonary hypertension and renal involvement.
format	Article
author	Teh, C. L. Kuan, Yeh Chunn Wong, J. S.
author_facet	Teh, C. L. Kuan, Yeh Chunn Wong, J. S.
author_sort	Teh, C. L.
title	Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
title_short	Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
title_full	Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
title_fullStr	Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
title_full_unstemmed	Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital
title_sort	systemic sclerosis in sarawak : a profile of patients trated in the sarawak general hospital
publisher	Springer
publishDate	2009
url	http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/ http://irep.iium.edu.my/17285/1/Kuan_RheuInt2009_systemic_sclerosis.pdf
first_indexed	2023-09-18T20:26:07Z
last_indexed	2023-09-18T20:26:07Z
_version_	1777408427572592640

Systemic sclerosis in Sarawak : a profile of patients trated in the Sarawak General Hospital

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