Parkinsonism complicating acute organophosphate insecticide poisoning

Organophosphate insecticides have a triphasic effect on the central nervous system, namely acute cholinergic crisis, intermediate syndrome and delayed polyneuropathy. Although acute organophosphate poisoning is relatively common, case reports describing parkinsonism as a neurological comp...

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Main Authors:	Hashim, Hasnur Zaman, Wan Musa, Wan Rosmaiza, Chai, Soon Ngiu, Wan Yahya, Wan Nafisah, Hui, Jan Tan, Ibrahim, Norlinah
Format:	Article
Language:	English
Published:	Academy of Medicine, Singapore 2011
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/18676/ http://irep.iium.edu.my/18676/ http://irep.iium.edu.my/18676/1/V40N3p150.pdf

id	iium-18676
recordtype	eprints
spelling	iium-186762012-03-14T02:24:34Z http://irep.iium.edu.my/18676/ Parkinsonism complicating acute organophosphate insecticide poisoning Hashim, Hasnur Zaman Wan Musa, Wan Rosmaiza Chai, Soon Ngiu Wan Yahya, Wan Nafisah Hui, Jan Tan Ibrahim, Norlinah R Medicine (General) Organophosphate insecticides have a triphasic effect on the central nervous system, namely acute cholinergic crisis, intermediate syndrome and delayed polyneuropathy. Although acute organophosphate poisoning is relatively common, case reports describing parkinsonism as a neurological complication following an acute intoxication are limited. 1 We report a case of parkinsonism noted on day 24 of admission following an acute severe organophosphate poisoning which was successfully treated with benzhexol and levodopa. Previously, response to levodopa was reported to be poor in 3 patients studied by Bhatt et al 1whereas amantidine, dopamine agonist and bipiriden have been shown to be helpful. 2To the best of our knowledge, this is the ﬁ rst case of parkinsonism complicating organophosphate poisoning which responded to levodopa and benzhexol therapy. Academy of Medicine, Singapore 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/18676/1/V40N3p150.pdf Hashim, Hasnur Zaman and Wan Musa, Wan Rosmaiza and Chai, Soon Ngiu and Wan Yahya, Wan Nafisah and Hui, Jan Tan and Ibrahim, Norlinah (2011) Parkinsonism complicating acute organophosphate insecticide poisoning. Annals Academy of Medicine Singapore, 40 (3). pp. 150-151. ISSN 0304-4602 http://www.annals.edu.sg/pdf/40VolNo3Mar2011/V40N3p150.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Hashim, Hasnur Zaman Wan Musa, Wan Rosmaiza Chai, Soon Ngiu Wan Yahya, Wan Nafisah Hui, Jan Tan Ibrahim, Norlinah Parkinsonism complicating acute organophosphate insecticide poisoning
description	Organophosphate insecticides have a triphasic effect on the central nervous system, namely acute cholinergic crisis, intermediate syndrome and delayed polyneuropathy. Although acute organophosphate poisoning is relatively common, case reports describing parkinsonism as a neurological complication following an acute intoxication are limited. 1 We report a case of parkinsonism noted on day 24 of admission following an acute severe organophosphate poisoning which was successfully treated with benzhexol and levodopa. Previously, response to levodopa was reported to be poor in 3 patients studied by Bhatt et al 1whereas amantidine, dopamine agonist and bipiriden have been shown to be helpful. 2To the best of our knowledge, this is the ﬁ rst case of parkinsonism complicating organophosphate poisoning which responded to levodopa and benzhexol therapy.
format	Article
author	Hashim, Hasnur Zaman Wan Musa, Wan Rosmaiza Chai, Soon Ngiu Wan Yahya, Wan Nafisah Hui, Jan Tan Ibrahim, Norlinah
author_facet	Hashim, Hasnur Zaman Wan Musa, Wan Rosmaiza Chai, Soon Ngiu Wan Yahya, Wan Nafisah Hui, Jan Tan Ibrahim, Norlinah
author_sort	Hashim, Hasnur Zaman
title	Parkinsonism complicating acute organophosphate insecticide poisoning
title_short	Parkinsonism complicating acute organophosphate insecticide poisoning
title_full	Parkinsonism complicating acute organophosphate insecticide poisoning
title_fullStr	Parkinsonism complicating acute organophosphate insecticide poisoning
title_full_unstemmed	Parkinsonism complicating acute organophosphate insecticide poisoning
title_sort	parkinsonism complicating acute organophosphate insecticide poisoning
publisher	Academy of Medicine, Singapore
publishDate	2011
url	http://irep.iium.edu.my/18676/ http://irep.iium.edu.my/18676/ http://irep.iium.edu.my/18676/1/V40N3p150.pdf
first_indexed	2023-09-18T20:27:50Z
last_indexed	2023-09-18T20:27:50Z
_version_	1777408536315166720

Parkinsonism complicating acute organophosphate insecticide poisoning

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