The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1

The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1

CYP2D6 plays a major role in the metabolism of tamoxifen, and polymorphism of Pglycoprotein has been associated with resistance of many drug therapies. This study investigates the clinical impact of genetic variants of CYP2D6 and ABCB1 in breast cancer patients treated with tamoxifen. Blood samples...

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Bibliographic Details
Main Authors: Teh, L. K., Mohammed, N.I, Salleh, M.Z., Rohaizak, M., Shahrun, N.S, Saladina, J.J., Shia, J.K.S., Roslan, H., Rajoo, T.S., Muniandy, S.P., Henry, G., Abdullah Ngow, Harris, Hla, K.T, Din, J
Format: Article
Language:English
Published: Springer 2011
Subjects:
R Medicine (General)
RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:http://irep.iium.edu.my/18761/
http://irep.iium.edu.my/18761/
http://irep.iium.edu.my/18761/1/The_risk_of_recurrence_in_breast_cancer_patients_treated_with_Tamoxifen_Polymorphisms_of_CYP2D6_and_ABCB1.pdf

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