Phytochemical and biological activity study of Calophyllum canum

Calophyllum canum or (Bintangor Batu) is a Malaysian plant which belongs to the family of Guttiferae. This family considered being a source of xanthons and flavonoids, which has shown lately the biological activity against bacterial, fungus and cancer cells. The most well known species Calophyllum I...

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Main Authors:	Alkhamaiseh, Suhaib Ibrahim, Bakhtiar, M. Taher, Ahmad , Farediah
Format:	Conference or Workshop Item
Language:	English
Published:	2010
Subjects:	R Medicine (General) RB Pathology
Online Access:	http://irep.iium.edu.my/19534/ http://irep.iium.edu.my/19534/ http://irep.iium.edu.my/19534/1/Phytochemical_and_biological.pdf

id	iium-19534
recordtype	eprints
spelling	iium-195342014-12-09T01:40:09Z http://irep.iium.edu.my/19534/ Phytochemical and biological activity study of Calophyllum canum Alkhamaiseh, Suhaib Ibrahim Bakhtiar, M. Taher Ahmad , Farediah R Medicine (General) RB Pathology Calophyllum canum or (Bintangor Batu) is a Malaysian plant which belongs to the family of Guttiferae. This family considered being a source of xanthons and flavonoids, which has shown lately the biological activity against bacterial, fungus and cancer cells. The most well known species Calophyllum Ianigerum which found in Sarawak shown a biological activity against human immunodeficiency virus (HIV). During the last three decades, the studies have been done for isolating these certain compounds. In this research we are concentrating on phytochemical study of C.canum. The stem bark of this plant dried and grinded to get a powder form, and then it has been extracted by using Soxhlet extraction method, where the extraction started with Hexane, Ethyl acetate and Methanol. The extracts were isolated by using Chromatography method (vacuum and column), the hexane and ethyl acetate fraction yield six pure compounds marker as (cc1-cc6). The crude extract examined against bacterial gram (positive and negative), by using the disk diffusion method. Also it has been tested to observe any antioxidant behaviors. As well as the crude and identified compounds will be tested for there anticancer activity against lung, leukemia, colon, breast and cervix cancer. The cell growth will be monitored by inhibition of cell proliferation with MTT assay. For the identification, we used the spectroscopic techniques (NMR, IR, MS, and UV/Vis) for interpretation the structure of these pure compounds. The results are under processing to draw the structure. 2010 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/19534/1/Phytochemical_and_biological.pdf Alkhamaiseh, Suhaib Ibrahim and Bakhtiar, M. Taher and Ahmad , Farediah (2010) Phytochemical and biological activity study of Calophyllum canum. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010, 27-29 November 2010, Vistana Hotel, Kuantan, Pahang. http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RB Pathology
spellingShingle	R Medicine (General) RB Pathology Alkhamaiseh, Suhaib Ibrahim Bakhtiar, M. Taher Ahmad , Farediah Phytochemical and biological activity study of Calophyllum canum
description	Calophyllum canum or (Bintangor Batu) is a Malaysian plant which belongs to the family of Guttiferae. This family considered being a source of xanthons and flavonoids, which has shown lately the biological activity against bacterial, fungus and cancer cells. The most well known species Calophyllum Ianigerum which found in Sarawak shown a biological activity against human immunodeficiency virus (HIV). During the last three decades, the studies have been done for isolating these certain compounds. In this research we are concentrating on phytochemical study of C.canum. The stem bark of this plant dried and grinded to get a powder form, and then it has been extracted by using Soxhlet extraction method, where the extraction started with Hexane, Ethyl acetate and Methanol. The extracts were isolated by using Chromatography method (vacuum and column), the hexane and ethyl acetate fraction yield six pure compounds marker as (cc1-cc6). The crude extract examined against bacterial gram (positive and negative), by using the disk diffusion method. Also it has been tested to observe any antioxidant behaviors. As well as the crude and identified compounds will be tested for there anticancer activity against lung, leukemia, colon, breast and cervix cancer. The cell growth will be monitored by inhibition of cell proliferation with MTT assay. For the identification, we used the spectroscopic techniques (NMR, IR, MS, and UV/Vis) for interpretation the structure of these pure compounds. The results are under processing to draw the structure.
format	Conference or Workshop Item
author	Alkhamaiseh, Suhaib Ibrahim Bakhtiar, M. Taher Ahmad , Farediah
author_facet	Alkhamaiseh, Suhaib Ibrahim Bakhtiar, M. Taher Ahmad , Farediah
author_sort	Alkhamaiseh, Suhaib Ibrahim
title	Phytochemical and biological activity study of Calophyllum canum
title_short	Phytochemical and biological activity study of Calophyllum canum
title_full	Phytochemical and biological activity study of Calophyllum canum
title_fullStr	Phytochemical and biological activity study of Calophyllum canum
title_full_unstemmed	Phytochemical and biological activity study of Calophyllum canum
title_sort	phytochemical and biological activity study of calophyllum canum
publishDate	2010
url	http://irep.iium.edu.my/19534/ http://irep.iium.edu.my/19534/ http://irep.iium.edu.my/19534/1/Phytochemical_and_biological.pdf
first_indexed	2023-09-18T20:29:10Z
last_indexed	2023-09-18T20:29:10Z
_version_	1777408619930714112

Phytochemical and biological activity study of Calophyllum canum

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