Improvement of extraction processing conditions for antibacterial compounds from Curcuma longa

Curcuma longa is a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae that is known for its antibacterial property. In this study optimization of extraction processing conditions were detemlined to obtain maximum yield of antibacterial compounds from C. longa. Optimization e...

Full description

Bibliographic Details
Main Authors: Ahmad Raus, Raha, Abdul Malek, Nur Farihah, Bastami, Mohd Saufi, Mat Amin, Noriha
Format: Book Chapter
Language:English
Published: IIUM Press 2011
Subjects:
Online Access:http://irep.iium.edu.my/20793/
http://irep.iium.edu.my/20793/
http://irep.iium.edu.my/20793/1/IMPROVEMENT_OF_EXTRACTION_PROCESSING_CONDITIONS_FOR_ANTIBACTERIAL_COMPOUNDS_FROM_Curcuma_longa.pdf
Description
Summary:Curcuma longa is a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae that is known for its antibacterial property. In this study optimization of extraction processing conditions were detemlined to obtain maximum yield of antibacterial compounds from C. longa. Optimization experiments designed by Box-Behnken (Design Expert Software) were carried out with three parameters considered namely agitation, extraction time and temperature. Analysis of results was done statistically using Analysis of Yariance (ANDYA). The regression equation analysis showed that the optimum condition in producing antibacterial compound \vas 40°C of temperature, 24 hour and at 150 rpm agitation speed gave the maximum diameter of zone inhibition (19.17 mm). The analysis showed that the model (p < 0.01) is significant for inhibiting the bacterial activity.