Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite

Recently, development of porous calcium phosphates ceramics has raised considerable interest. A porous structure promotes cell attachment, proliferation and provides pathways for biofluids. Therefore, a high porosity with interconnected pore structure generally favors tissue regeneration. In this wo...

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Main Authors:	Sopyan, Iis, Che Murad, Mardziah, Singh, Ramesh
Format:	Article
Language:	English
Published:	Trans Tech Publications Ltd., Switzerland 2012
Subjects:	TA Engineering (General). Civil engineering (General)
Online Access:	http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/1/AMM-1.117-119.829_6.pdf

id	iium-21422
recordtype	eprints
spelling	iium-214222012-12-27T23:33:42Z http://irep.iium.edu.my/21422/ Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite Sopyan, Iis Che Murad, Mardziah Singh, Ramesh TA Engineering (General). Civil engineering (General) Recently, development of porous calcium phosphates ceramics has raised considerable interest. A porous structure promotes cell attachment, proliferation and provides pathways for biofluids. Therefore, a high porosity with interconnected pore structure generally favors tissue regeneration. In this work, replication of 0, 2, 5, 10 and 15% SrHA (strontium-doped hydroxyapatite) porous scaffolds via polymeric sponge method has been employed using the sol-gel derived SrHA powders. To prepare the porous samples, the synthesized SrHA powders were mixed with distilled water and dispersing agent followed by drying in the ambient air and specific sintering process. Morphological evaluation by FESEM measurement revealed that the SrHA scaffolds were characterized by macro-micro interconnected porosity, which replicates the morphology of the cancellous bone. Compression test on the porous scaffolds revealed that doping 10 mol% of strontium in HA has increased the compressive strength by a factor of two compared to the undoped HA with 1.81±0.26 MPa at 41% porosity. Trans Tech Publications Ltd., Switzerland 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/21422/1/AMM-1.117-119.829_6.pdf Sopyan, Iis and Che Murad, Mardziah and Singh, Ramesh (2012) Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite. Applied Mechanics and Materials, 117-19. pp. 829-832. ISSN 1660-9336 http://www.scientific.net/AMM.117-119.829 10.4028/www.scientific.net/AMM.117-119.829
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TA Engineering (General). Civil engineering (General)
spellingShingle	TA Engineering (General). Civil engineering (General) Sopyan, Iis Che Murad, Mardziah Singh, Ramesh Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
description	Recently, development of porous calcium phosphates ceramics has raised considerable interest. A porous structure promotes cell attachment, proliferation and provides pathways for biofluids. Therefore, a high porosity with interconnected pore structure generally favors tissue regeneration. In this work, replication of 0, 2, 5, 10 and 15% SrHA (strontium-doped hydroxyapatite) porous scaffolds via polymeric sponge method has been employed using the sol-gel derived SrHA powders. To prepare the porous samples, the synthesized SrHA powders were mixed with distilled water and dispersing agent followed by drying in the ambient air and specific sintering process. Morphological evaluation by FESEM measurement revealed that the SrHA scaffolds were characterized by macro-micro interconnected porosity, which replicates the morphology of the cancellous bone. Compression test on the porous scaffolds revealed that doping 10 mol% of strontium in HA has increased the compressive strength by a factor of two compared to the undoped HA with 1.81±0.26 MPa at 41% porosity.
format	Article
author	Sopyan, Iis Che Murad, Mardziah Singh, Ramesh
author_facet	Sopyan, Iis Che Murad, Mardziah Singh, Ramesh
author_sort	Sopyan, Iis
title	Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
title_short	Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
title_full	Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
title_fullStr	Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
title_full_unstemmed	Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
title_sort	fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite
publisher	Trans Tech Publications Ltd., Switzerland
publishDate	2012
url	http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/ http://irep.iium.edu.my/21422/1/AMM-1.117-119.829_6.pdf
first_indexed	2023-09-18T20:32:32Z
last_indexed	2023-09-18T20:32:32Z
_version_	1777408831629819904

Fabrication of porous ceramic scaffolds via polymeric sponge method using sol-gel derived strontium doped hydroxyapatite

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