Pharmacogenetics of beta adrenergic blockers: their clinical significance

Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, t...

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Main Author:	Elsayed, Tarek Mohamed Ali
Format:	Article
Language:	English
Published:	USM 2009
Subjects:	RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf

id	iium-22234
recordtype	eprints
spelling	iium-222342016-11-06T04:31:08Z http://irep.iium.edu.my/22234/ Pharmacogenetics of beta adrenergic blockers: their clinical significance Elsayed, Tarek Mohamed Ali RM300 Drugs and their action Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, tremor, and glaucoma. Individual and ethnic variability has been noted in clinical practice and reported in clinical trials. Many factors are anticipated to affect the extent of variability of response to β-blockers including pharmacodynamic variability and pharmacokinetic variability of the parent compounds, as well as, active constituents. In this review, we will present the studies that examine the effect of genetic variability on the pharmacodynamics of β-blockers. USM 2009-12 Article NonPeerReviewed application/pdf en http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf Elsayed, Tarek Mohamed Ali (2009) Pharmacogenetics of beta adrenergic blockers: their clinical significance. INFORMM: Postgraduate Bulletin, 1 (4). pp. 20-23. ISSN 2180-1959 http://www.informm.usm.my/index.php/en/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RM300 Drugs and their action
spellingShingle	RM300 Drugs and their action Elsayed, Tarek Mohamed Ali Pharmacogenetics of beta adrenergic blockers: their clinical significance
description	Beta adrenergic blockers are (ß-blockers) an important class of drugs for the treatment of various cardiovascular diseases, including hypertension, angina pectoris, arrhythmias, hypertrophic cardiomyopathy, and heart failure. They are also indicated for the treatment of migraine headache, anxiety, tremor, and glaucoma. Individual and ethnic variability has been noted in clinical practice and reported in clinical trials. Many factors are anticipated to affect the extent of variability of response to β-blockers including pharmacodynamic variability and pharmacokinetic variability of the parent compounds, as well as, active constituents. In this review, we will present the studies that examine the effect of genetic variability on the pharmacodynamics of β-blockers.
format	Article
author	Elsayed, Tarek Mohamed Ali
author_facet	Elsayed, Tarek Mohamed Ali
author_sort	Elsayed, Tarek Mohamed Ali
title	Pharmacogenetics of beta adrenergic blockers: their clinical significance
title_short	Pharmacogenetics of beta adrenergic blockers: their clinical significance
title_full	Pharmacogenetics of beta adrenergic blockers: their clinical significance
title_fullStr	Pharmacogenetics of beta adrenergic blockers: their clinical significance
title_full_unstemmed	Pharmacogenetics of beta adrenergic blockers: their clinical significance
title_sort	pharmacogenetics of beta adrenergic blockers: their clinical significance
publisher	USM
publishDate	2009
url	http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/ http://irep.iium.edu.my/22234/1/Buletin_no.4.pdf
first_indexed	2023-09-18T20:33:58Z
last_indexed	2023-09-18T20:33:58Z
_version_	1777408921720324096

Pharmacogenetics of beta adrenergic blockers: their clinical significance

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