Potentially reversible causes of dementia

Introduction: Dementia is tragic mind-wrecking disease, defined as a multifaceted decline in cognitive function severe enough to interfere with activities of daily life. Three individual cases are presented that presented with loss of memory and altered behaviour. Even though potentially reversible...

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Main Authors: Rathor, Mohammad Yousuf, Abdul Rani, Mohammed Fauzi, Wai, Kyaw Thun, Abdul Rashid, Mohd Amran, Akter, Seikh Farid Uddin, Musa, Ramli
Format: Article
Language:English
Published: International Online Medical Council (IOMC) 2010
Subjects:
Online Access:http://irep.iium.edu.my/232/
http://irep.iium.edu.my/232/
http://irep.iium.edu.my/232/1/Potentially_reversible_causes_of_Dementia.pdf
id iium-232
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spelling iium-2322014-07-10T04:34:35Z http://irep.iium.edu.my/232/ Potentially reversible causes of dementia Rathor, Mohammad Yousuf Abdul Rani, Mohammed Fauzi Wai, Kyaw Thun Abdul Rashid, Mohd Amran Akter, Seikh Farid Uddin Musa, Ramli RC Internal medicine Introduction: Dementia is tragic mind-wrecking disease, defined as a multifaceted decline in cognitive function severe enough to interfere with activities of daily life. Three individual cases are presented that presented with loss of memory and altered behaviour. Even though potentially reversible dementia accounts for a relatively small portion of the total cases of dementia, the three cases presented here demonstrate that accurate and timely diagnosis may greatly improve the condition of the patients, or even restore their normal intellectual function. Case presentation: Patients 69 year old Malay male and 79 year old Chinese male were brought in to our hospital by their families with history of memory impairment and altered behaviour. The former was diagnosed as left frontoparietal meningioma with possible haemorrhage causing mass effect. The latter was diagnosed as subdural hematoma with midline shift. The former underwent craniotomy and excision of meningioma, and aspiration of an adjacent hemorrhagic cyst. The latter underwent burr-hole craniotomy with closed-system drainage. Following surgery both patients improved with Mini-Mental State Examination levels (MMSE) of 28/30 and 30/30 respectively and in their follow-up were doing well. Third patient, a 50-year-old Chinese lady, had symptoms of forgetfulness and altered behaviour for the past two years, was treated for depression and improved markedly with no more psychotic symptoms. Conclusion: Chronic subdural hematomas, meningiomas and depression are among the known reversible causes of dementia. Presenting symptoms can be subtle and clinical acumen dictates that all patients should be thoroughly investigated to rule out such possibilities. International Online Medical Council (IOMC) 2010 Article PeerReviewed application/pdf en http://irep.iium.edu.my/232/1/Potentially_reversible_causes_of_Dementia.pdf Rathor, Mohammad Yousuf and Abdul Rani, Mohammed Fauzi and Wai, Kyaw Thun and Abdul Rashid, Mohd Amran and Akter, Seikh Farid Uddin and Musa, Ramli (2010) Potentially reversible causes of dementia. International Journal of Collaborative Research on Internal Medicine & Public Health, 2 (8). pp. 258-265. ISSN 1840-4529 http://www.iomcworld.com/ijcrimph/files/v02-n08-01.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RC Internal medicine
spellingShingle RC Internal medicine
Rathor, Mohammad Yousuf
Abdul Rani, Mohammed Fauzi
Wai, Kyaw Thun
Abdul Rashid, Mohd Amran
Akter, Seikh Farid Uddin
Musa, Ramli
Potentially reversible causes of dementia
description Introduction: Dementia is tragic mind-wrecking disease, defined as a multifaceted decline in cognitive function severe enough to interfere with activities of daily life. Three individual cases are presented that presented with loss of memory and altered behaviour. Even though potentially reversible dementia accounts for a relatively small portion of the total cases of dementia, the three cases presented here demonstrate that accurate and timely diagnosis may greatly improve the condition of the patients, or even restore their normal intellectual function. Case presentation: Patients 69 year old Malay male and 79 year old Chinese male were brought in to our hospital by their families with history of memory impairment and altered behaviour. The former was diagnosed as left frontoparietal meningioma with possible haemorrhage causing mass effect. The latter was diagnosed as subdural hematoma with midline shift. The former underwent craniotomy and excision of meningioma, and aspiration of an adjacent hemorrhagic cyst. The latter underwent burr-hole craniotomy with closed-system drainage. Following surgery both patients improved with Mini-Mental State Examination levels (MMSE) of 28/30 and 30/30 respectively and in their follow-up were doing well. Third patient, a 50-year-old Chinese lady, had symptoms of forgetfulness and altered behaviour for the past two years, was treated for depression and improved markedly with no more psychotic symptoms. Conclusion: Chronic subdural hematomas, meningiomas and depression are among the known reversible causes of dementia. Presenting symptoms can be subtle and clinical acumen dictates that all patients should be thoroughly investigated to rule out such possibilities.
format Article
author Rathor, Mohammad Yousuf
Abdul Rani, Mohammed Fauzi
Wai, Kyaw Thun
Abdul Rashid, Mohd Amran
Akter, Seikh Farid Uddin
Musa, Ramli
author_facet Rathor, Mohammad Yousuf
Abdul Rani, Mohammed Fauzi
Wai, Kyaw Thun
Abdul Rashid, Mohd Amran
Akter, Seikh Farid Uddin
Musa, Ramli
author_sort Rathor, Mohammad Yousuf
title Potentially reversible causes of dementia
title_short Potentially reversible causes of dementia
title_full Potentially reversible causes of dementia
title_fullStr Potentially reversible causes of dementia
title_full_unstemmed Potentially reversible causes of dementia
title_sort potentially reversible causes of dementia
publisher International Online Medical Council (IOMC)
publishDate 2010
url http://irep.iium.edu.my/232/
http://irep.iium.edu.my/232/
http://irep.iium.edu.my/232/1/Potentially_reversible_causes_of_Dementia.pdf
first_indexed 2023-09-18T20:07:20Z
last_indexed 2023-09-18T20:07:20Z
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