Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar

As serodiagnosis is the easiest way of diagnosing a disease, the utility of (Major Membrane Protein II) MMP-II antigen in the serodiagnosis of leprosy was examined and compared with NTP-BSA ELISA test. It was carried out on the blood samples of new leprosy cases and their contacts from Nyaungdon Tow...

Full description

Bibliographic Details
Main Authors:	Khin, Nwe Oo, Mi Htwe, Mi, Khine Zar, Win, Khin Thet, Wai, Kyaw, Myint, Kyaw, Kyaw
Format:	Article
Language:	English
Published:	2009
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/23294/ http://irep.iium.edu.my/23294/ http://irep.iium.edu.my/23294/1/n26_51.pdf

id	iium-23294
recordtype	eprints
spelling	iium-232942013-03-22T08:46:29Z http://irep.iium.edu.my/23294/ Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar Khin, Nwe Oo Mi Htwe, Mi Khine Zar, Win Khin Thet, Wai Kyaw, Myint Kyaw, Kyaw R Medicine (General) As serodiagnosis is the easiest way of diagnosing a disease, the utility of (Major Membrane Protein II) MMP-II antigen in the serodiagnosis of leprosy was examined and compared with NTP-BSA ELISA test. It was carried out on the blood samples of new leprosy cases and their contacts from Nyaungdon Township, and on new adult pulmonary TB cases of Yangon TB Center and childhood TB cases of Yangon Children's Hospital and North Okkalapa General Hospital between November 2006 and December 2007. The sensitivity of the tests on detecting leprosy patients who had not been treated was 58/77 (75.32%) and 54/77 (70.1%) for MB patients using MMP-II and NTP-BSA ELISA tests, respectively. It was 48/64 (75.0%) and 40/64 (62.50%) for PB patients using MMP-II and NTP-BSA ELISA tests, respectively. The sensitivity of MMP-II ELISA test was higher than that of NTP-BSA ELISA test on both leprosy patients. The sensitivity of MMP-II ELISA test was also higher than that of NTP-BSA ELISA test on TB patients in our study. Therefore, our data indicate that MMP-II ELISA could be useful as a supporting serodiagnostic tool in diagnosis of leprosy and childhood tuberculosis 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/23294/1/n26_51.pdf Khin, Nwe Oo and Mi Htwe, Mi and Khine Zar, Win and Khin Thet, Wai and Kyaw, Myint and Kyaw, Kyaw (2009) Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar. Myanmar Health Sciences Research Journal, 21 (3). pp. 121-125. ISSN 1015-0781 http://www.cabdirect.org/abstracts/20103291627.html;jsessionid=9E9DCA9F0B6873942DF160636614D96B
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Khin, Nwe Oo Mi Htwe, Mi Khine Zar, Win Khin Thet, Wai Kyaw, Myint Kyaw, Kyaw Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
description	As serodiagnosis is the easiest way of diagnosing a disease, the utility of (Major Membrane Protein II) MMP-II antigen in the serodiagnosis of leprosy was examined and compared with NTP-BSA ELISA test. It was carried out on the blood samples of new leprosy cases and their contacts from Nyaungdon Township, and on new adult pulmonary TB cases of Yangon TB Center and childhood TB cases of Yangon Children's Hospital and North Okkalapa General Hospital between November 2006 and December 2007. The sensitivity of the tests on detecting leprosy patients who had not been treated was 58/77 (75.32%) and 54/77 (70.1%) for MB patients using MMP-II and NTP-BSA ELISA tests, respectively. It was 48/64 (75.0%) and 40/64 (62.50%) for PB patients using MMP-II and NTP-BSA ELISA tests, respectively. The sensitivity of MMP-II ELISA test was higher than that of NTP-BSA ELISA test on both leprosy patients. The sensitivity of MMP-II ELISA test was also higher than that of NTP-BSA ELISA test on TB patients in our study. Therefore, our data indicate that MMP-II ELISA could be useful as a supporting serodiagnostic tool in diagnosis of leprosy and childhood tuberculosis
format	Article
author	Khin, Nwe Oo Mi Htwe, Mi Khine Zar, Win Khin Thet, Wai Kyaw, Myint Kyaw, Kyaw
author_facet	Khin, Nwe Oo Mi Htwe, Mi Khine Zar, Win Khin Thet, Wai Kyaw, Myint Kyaw, Kyaw
author_sort	Khin, Nwe Oo
title	Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
title_short	Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
title_full	Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
title_fullStr	Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
title_full_unstemmed	Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar
title_sort	application of new serological (major membrane protein ii) enzyme linked immunosorbent assay for leprosy patients in myanmar
publishDate	2009
url	http://irep.iium.edu.my/23294/ http://irep.iium.edu.my/23294/ http://irep.iium.edu.my/23294/1/n26_51.pdf
first_indexed	2023-09-18T20:35:18Z
last_indexed	2023-09-18T20:35:18Z
_version_	1777409005693435904

Application of new serological (Major Membrane Protein II) enzyme linked immunosorbent assay for leprosy patients in Myanmar

Similar Items