Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid
The biotransformation of linoleic acid 1 using immobilised soybean lipoxygenase in a dimethyl sulfoxide (DMSO) containing medium followed by sodium borohydride reduction afforded 13(S)-hydroxy-octadeca-9(Z),11(E)-dienoic acid 13(S)-HODE 2 in 69% yield. After methylation, methyl 13(S)-HODE was subjec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Asian Network for Scientific Information
2007
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/24445/ http://irep.iium.edu.my/24445/ http://irep.iium.edu.my/24445/1/Biotransformation_and_stereoselective_synthesis_of_pharmaceutical_molecules_from_linoleic_acid.pdf |