Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia

Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia

Objective : Younger patients with sleep apnea have higher risks of cardiovascular mortality compared to their normal counterpart. Yet, it remains a continued struggle to find a suitable cost-effective means of screening for sleep apnea in the young population. We conducted a case-control study of t...

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Main Authors: Asha'ari, Zamzil Amin, Hasmoni, Mohamed Hadzri, Ab Rahman, Jamalludin, Raja Lope Ahmad, Raja Ahmad Al'konee
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
RF Otorhinolaryngology
Online Access:http://irep.iium.edu.my/24502/
http://irep.iium.edu.my/24502/1/Binder1.pdf
id iium-24502
recordtype eprints
spelling iium-245022016-03-10T06:57:52Z http://irep.iium.edu.my/24502/ Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia Asha'ari, Zamzil Amin Hasmoni, Mohamed Hadzri Ab Rahman, Jamalludin Raja Lope Ahmad, Raja Ahmad Al'konee RF Otorhinolaryngology Objective : Younger patients with sleep apnea have higher risks of cardiovascular mortality compared to their normal counterpart. Yet, it remains a continued struggle to find a suitable cost-effective means of screening for sleep apnea in the young population. We conducted a case-control study of the possible association between sleep apnea and hypertension in a younger population in Malaysia. Method : We analyzed data on sleep disordered breathing (based on a polysomnography study), body mass index (BMI), neck circumference, upper airway size, habitus and health history in 90 hypertensive and 90 non-hypertensive participants in a clinic-based setting. Independent t-test, chi-square, multivariate analysis and binary logistic regression models were used for case-control comparison. Results : The mean age of the participants was 28 years; 69.5 percent were men. The incidence and severity of sleep apnea were significantly higher in the hypertensive subjects than the control’s. Persons with sleep apnea (AHI 5 or more events/hour) had odds ratio 2.76 (95% confidence interval 1.57-4.86) and persons with severe sleep apnea (AHI 30 or more events/hour) had odds ratio 7.94 (95% confidence interval 4.21-15.33) of having hypertension than did persons without sleep apnea. Although adjustments for the compounding factors, particularly the BMI decreased the odds ratio to a large degree, subjects with severe sleep apnea were still 72% more likely to have hypertension than subjects without sleep apnea. Conclusion : Sleep apnea is associated with hypertension in the young adult in Malaysia. The association was more pronounced with the increasing severity of sleep apnea. Screening for sleep apnea should be considered in young adult with hypertension. 2012-06 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/24502/1/Binder1.pdf Asha'ari, Zamzil Amin and Hasmoni, Mohamed Hadzri and Ab Rahman, Jamalludin and Raja Lope Ahmad, Raja Ahmad Al'konee (2012) Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia. In: 4th Malaysian International ORL-HNS Congress & Inaugural ASEAN Sleep Congress, 28-30 June 2012, KL Convention Centre.
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RF Otorhinolaryngology
spellingShingle RF Otorhinolaryngology
Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Raja Lope Ahmad, Raja Ahmad Al'konee
Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
description Objective : Younger patients with sleep apnea have higher risks of cardiovascular mortality compared to their normal counterpart. Yet, it remains a continued struggle to find a suitable cost-effective means of screening for sleep apnea in the young population. We conducted a case-control study of the possible association between sleep apnea and hypertension in a younger population in Malaysia. Method : We analyzed data on sleep disordered breathing (based on a polysomnography study), body mass index (BMI), neck circumference, upper airway size, habitus and health history in 90 hypertensive and 90 non-hypertensive participants in a clinic-based setting. Independent t-test, chi-square, multivariate analysis and binary logistic regression models were used for case-control comparison. Results : The mean age of the participants was 28 years; 69.5 percent were men. The incidence and severity of sleep apnea were significantly higher in the hypertensive subjects than the control’s. Persons with sleep apnea (AHI 5 or more events/hour) had odds ratio 2.76 (95% confidence interval 1.57-4.86) and persons with severe sleep apnea (AHI 30 or more events/hour) had odds ratio 7.94 (95% confidence interval 4.21-15.33) of having hypertension than did persons without sleep apnea. Although adjustments for the compounding factors, particularly the BMI decreased the odds ratio to a large degree, subjects with severe sleep apnea were still 72% more likely to have hypertension than subjects without sleep apnea. Conclusion : Sleep apnea is associated with hypertension in the young adult in Malaysia. The association was more pronounced with the increasing severity of sleep apnea. Screening for sleep apnea should be considered in young adult with hypertension.
format Conference or Workshop Item
author Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Raja Lope Ahmad, Raja Ahmad Al'konee
author_facet Asha'ari, Zamzil Amin
Hasmoni, Mohamed Hadzri
Ab Rahman, Jamalludin
Raja Lope Ahmad, Raja Ahmad Al'konee
author_sort Asha'ari, Zamzil Amin
title Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
title_short Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
title_full Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
title_fullStr Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
title_full_unstemmed Screening for sleep apnea in the young hypertensive: evidence from a case-control study in Malaysia
title_sort screening for sleep apnea in the young hypertensive: evidence from a case-control study in malaysia
publishDate 2012
url http://irep.iium.edu.my/24502/
http://irep.iium.edu.my/24502/1/Binder1.pdf
first_indexed 2023-09-18T20:36:44Z
last_indexed 2023-09-18T20:36:44Z
_version_ 1777409095604633600

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