Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a...
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| Format: | Article |
| Language: | English |
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Elsevier
2010
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| Online Access: | http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf |
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iium-2638 |
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iium-26382011-12-20T08:44:29Z http://irep.iium.edu.my/2638/ Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia Caillaud, A de la Iglesia, P Campa` s, M Elandaloussi, L Ferna´ndez, M Mohammad Noor, Normawaty Andree, K Dioge`ne, J QD Chemistry SH Aquaculture. Fisheries. Angling Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a weak toxicity to the Neuro-2a CBA were also observed. Elsevier 2010 Article PeerReviewed application/pdf en http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf Caillaud, A and de la Iglesia, P and Campa` s, M and Elandaloussi, L and Ferna´ndez, M and Mohammad Noor, Normawaty and Andree, K and Dioge`ne, J (2010) Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia. Toxicon, 55. pp. 633-637. ISSN 0041-0101 http://www.elsevier.com/locate/toxicon |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
QD Chemistry SH Aquaculture. Fisheries. Angling |
| spellingShingle |
QD Chemistry SH Aquaculture. Fisheries. Angling Caillaud, A de la Iglesia, P Campa` s, M Elandaloussi, L Ferna´ndez, M Mohammad Noor, Normawaty Andree, K Dioge`ne, J Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| description |
Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by
a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a weak toxicity to the Neuro-2a CBA were also observed. |
| format |
Article |
| author |
Caillaud, A de la Iglesia, P Campa` s, M Elandaloussi, L Ferna´ndez, M Mohammad Noor, Normawaty Andree, K Dioge`ne, J |
| author_facet |
Caillaud, A de la Iglesia, P Campa` s, M Elandaloussi, L Ferna´ndez, M Mohammad Noor, Normawaty Andree, K Dioge`ne, J |
| author_sort |
Caillaud, A |
| title |
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| title_short |
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| title_full |
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| title_fullStr |
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| title_full_unstemmed |
Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia |
| title_sort |
evidence of okadaic acid production in a cultured strain of the marine dinoflagellate prorocentrum rhathymum from malaysia |
| publisher |
Elsevier |
| publishDate |
2010 |
| url |
http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf |
| first_indexed |
2023-09-18T20:10:15Z |
| last_indexed |
2023-09-18T20:10:15Z |
| _version_ |
1777407429527470080 |