Evidence of okadaic acid production in a cultured strain of the marine dinoflagellate Prorocentrum rhathymum from Malaysia
Protein phosphatase inhibition assay (PPIA), Neuroblastoma cell-based assay (Neuro-2a CBA)and LC-MS/MS analysis revealed for the first time the production of okadaic acid (OA) by a Prorocentrum rhathymum strain. Low amounts of OA were detected by LC-MS/MS analysis.Inhibition of PP2A activity and a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2010
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/ http://irep.iium.edu.my/2638/1/P-rhathymum_-Toxicon.pdf |