Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)

Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)

Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial...

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Main Authors: Myint, Yi Yi, Tun, Ye, Muhamad Amjad, Nasser, Mat Hassan, Mohd Zailani, Rashid, N.L
Format: Article
Language:English
Published: Microscopy Society of Malaysia 2012
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/27252/
http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf
id iium-27252
recordtype eprints
spelling iium-272522012-12-05T06:56:27Z http://irep.iium.edu.my/27252/ Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM) Myint, Yi Yi Tun, Ye Muhamad Amjad, Nasser Mat Hassan, Mohd Zailani Rashid, N.L R Medicine (General) Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore intercellular communications superficial esophageal cells in non- erosive reflux disease (NERD) patients. The study group included eight (NERD) patients and five normal controls individuals. Specimens were routinely processed for SEM observations. The nature of intercellular attachments and intercellular spaces between each individual superficial cells of the esophageal mucosa were viewed under SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings seems to support the concept of abnormal tissue resistance in the pathogenesis of NERD patients. Microscopy Society of Malaysia 2012-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf Myint, Yi Yi and Tun, Ye and Muhamad Amjad, Nasser and Mat Hassan, Mohd Zailani and Rashid, N.L (2012) Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM). Malaysian Journal of Microscopy, 8. pp. 139-142. ISSN 1823-7010
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Myint, Yi Yi
Tun, Ye
Muhamad Amjad, Nasser
Mat Hassan, Mohd Zailani
Rashid, N.L
Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
description Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to explore intercellular communications superficial esophageal cells in non- erosive reflux disease (NERD) patients. The study group included eight (NERD) patients and five normal controls individuals. Specimens were routinely processed for SEM observations. The nature of intercellular attachments and intercellular spaces between each individual superficial cells of the esophageal mucosa were viewed under SEM. Our results showed that cellular attachments in the superficial cells differ significantly (p value 0.007) among the normal controls and patients with NERD (Chi-Square test, p <0.05 was considered to be statistically significant). Our findings seems to support the concept of abnormal tissue resistance in the pathogenesis of NERD patients.
format Article
author Myint, Yi Yi
Tun, Ye
Muhamad Amjad, Nasser
Mat Hassan, Mohd Zailani
Rashid, N.L
author_facet Myint, Yi Yi
Tun, Ye
Muhamad Amjad, Nasser
Mat Hassan, Mohd Zailani
Rashid, N.L
author_sort Myint, Yi Yi
title Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
title_short Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
title_full Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
title_fullStr Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
title_full_unstemmed Esophageal surface cells in non-erosive reflux disease: A Scanning Electron Microscopical study (SEM)
title_sort esophageal surface cells in non-erosive reflux disease: a scanning electron microscopical study (sem)
publisher Microscopy Society of Malaysia
publishDate 2012
url http://irep.iium.edu.my/27252/
http://irep.iium.edu.my/27252/1/Esophageal_Reflux_Disease.pdf
first_indexed 2023-09-18T20:40:32Z
last_indexed 2023-09-18T20:40:32Z
_version_ 1777409334873948160

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