Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital

Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children pre...

Full description

Bibliographic Details
Main Authors: Nagi, Abdul Ghaffar, Murad, Raffat, Baig, Mukhtiar
Format: Article
Language:English
Published: Bahria University Medical & Dental College 2011
Subjects:
Online Access:http://irep.iium.edu.my/28688/
http://irep.iium.edu.my/28688/
http://irep.iium.edu.my/28688/1/JBUMDC.pdf
id iium-28688
recordtype eprints
spelling iium-286882013-02-13T09:24:29Z http://irep.iium.edu.my/28688/ Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital Nagi, Abdul Ghaffar Murad, Raffat Baig, Mukhtiar RJ Pediatrics Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children presented with fever and presence of at least 2 clinical manifestations of suspected dengue infection according to WHO criteria were included in study. Patients were followed regarding clinical presentation, investigations, management and outcome. Results: A total of 152 children admitted with suspicion of having dengue fever were evaluated in the study. Dengue fever antibody IgM tested on all suspected patients along with CBC, PT/aPTT, Blood C/S, Serum protein and chest X- ray. Dengue fever IgM was positive in 111 patients. A significant majority of dengue patients belonged to peri urban slums. Common presenting symptom among dengue patients was fever (100%), rash (71.17%), vomiting (52.25%), hemorrhagic manifestation (36.03%) and fits (5.40%). Among 111 dengue positive cases 65 (58.58%) were Dengue Fever (DF) cases, 40 (36.03%) were Dengue Hemorrhagic Fever (DHF) and 6 (5.4%) were cases of Dengue Shock Syndrome (DSS). Three patients expired during their stay in hospital. Conclusion: A high percentage of dengue positive cases among suspected patients and a significant proportion of dengue hemorrhagic fever and dengue shock syndrome cases demands careful investigation and management. Bahria University Medical & Dental College 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/28688/1/JBUMDC.pdf Nagi, Abdul Ghaffar and Murad, Raffat and Baig, Mukhtiar (2011) Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital. The Journal of Bahria University Medical and Dental College, 1 (2). pp. 44-48. ISSN 2220-7562 http://www.bahria.edu.pk/newSite/JBUMDC-2.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RJ Pediatrics
spellingShingle RJ Pediatrics
Nagi, Abdul Ghaffar
Murad, Raffat
Baig, Mukhtiar
Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
description Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children presented with fever and presence of at least 2 clinical manifestations of suspected dengue infection according to WHO criteria were included in study. Patients were followed regarding clinical presentation, investigations, management and outcome. Results: A total of 152 children admitted with suspicion of having dengue fever were evaluated in the study. Dengue fever antibody IgM tested on all suspected patients along with CBC, PT/aPTT, Blood C/S, Serum protein and chest X- ray. Dengue fever IgM was positive in 111 patients. A significant majority of dengue patients belonged to peri urban slums. Common presenting symptom among dengue patients was fever (100%), rash (71.17%), vomiting (52.25%), hemorrhagic manifestation (36.03%) and fits (5.40%). Among 111 dengue positive cases 65 (58.58%) were Dengue Fever (DF) cases, 40 (36.03%) were Dengue Hemorrhagic Fever (DHF) and 6 (5.4%) were cases of Dengue Shock Syndrome (DSS). Three patients expired during their stay in hospital. Conclusion: A high percentage of dengue positive cases among suspected patients and a significant proportion of dengue hemorrhagic fever and dengue shock syndrome cases demands careful investigation and management.
format Article
author Nagi, Abdul Ghaffar
Murad, Raffat
Baig, Mukhtiar
author_facet Nagi, Abdul Ghaffar
Murad, Raffat
Baig, Mukhtiar
author_sort Nagi, Abdul Ghaffar
title Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
title_short Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
title_full Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
title_fullStr Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
title_full_unstemmed Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital
title_sort dengue fever outbreak among children in karachi : experience at a tertiary care children hospital
publisher Bahria University Medical & Dental College
publishDate 2011
url http://irep.iium.edu.my/28688/
http://irep.iium.edu.my/28688/
http://irep.iium.edu.my/28688/1/JBUMDC.pdf
first_indexed 2023-09-18T20:42:14Z
last_indexed 2023-09-18T20:42:14Z
_version_ 1777409441956626432