Extraction and evaluation of antibacterial activity from selected flowering plants

The huge diversity of Malaysian flora has various chemical constituents that make them as outstanding natural product candidates for the treatment of infectious diseases. The screening practice for phytochemical compound in them is essential to explore more natural sources to replace synthetic an...

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Main Authors:	Abdullah, Erlina, Ahmad Raus, Raha, Jamal, Parveen
Format:	Article
Language:	English
Published:	Science Publications 2012
Subjects:	TX341 Nutrition. Foods and food supply
Online Access:	http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/1/Abdullah_et_al_American_Medical_J.pdf

id	iium-29228
recordtype	eprints
spelling	iium-292282013-03-14T03:54:54Z http://irep.iium.edu.my/29228/ Extraction and evaluation of antibacterial activity from selected flowering plants Abdullah, Erlina Ahmad Raus, Raha Jamal, Parveen TX341 Nutrition. Foods and food supply The huge diversity of Malaysian flora has various chemical constituents that make them as outstanding natural product candidates for the treatment of infectious diseases. The screening practice for phytochemical compound in them is essential to explore more natural sources to replace synthetic antibiotics, which generally have side effects such as hypersensitivity, immune-suppression and allergic reactions. Antibacterial activities have been detected in some of the Malaysian plants and most of the Malaysian medicinal plants have been screened for this property. However, so far no study has focus on Malaysian flowering plants yet. In this study, the extraction and determination of antibacterial property from 19 Malaysian flowering plants were conducted. The plants were extracted with methanol, ethyl acetate, hexane and distilled water, individually at concentration of 0.1g mL-1. The extraction process condition was set to 300 rpm agitation for 10 h at room temperature. The crude extracts of each plant (5 mg/disc) were tested against Bacillus subtilis and Escherichia coli using agar disc diffusion assay method. The screening results showed that ethyl acetate extract of Spathiphyllum cannifolium (‘peace lily’) leaves possesses the highest antibacterial activity against B. subtilis with zone of inhibition of 25 mm. Most of the plant samples extracted with methanol and ethyl acetate have indicated positive activity toward B. subtilis growth. However, the hexane and distilled water extracts was ineffective to combat the B. subtilis growth. Unfortunately, all of the extracts were not active against E. coli. This study suggested that S. cannifolium is highly potential in antibacterial activity which can be further analyzed for the development of new antibiotic exclusively for gram positive bacteria. Science Publications 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29228/1/Abdullah_et_al_American_Medical_J.pdf Abdullah, Erlina and Ahmad Raus, Raha and Jamal, Parveen (2012) Extraction and evaluation of antibacterial activity from selected flowering plants. American Medical Journal, 3 (1). pp. 27-32. ISSN 1949-0070 http://thescipub.com/abstract/10.3844/amjsp.2012.27.32 10.3844/amjsp.2012.27.32
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TX341 Nutrition. Foods and food supply
spellingShingle	TX341 Nutrition. Foods and food supply Abdullah, Erlina Ahmad Raus, Raha Jamal, Parveen Extraction and evaluation of antibacterial activity from selected flowering plants
description	The huge diversity of Malaysian flora has various chemical constituents that make them as outstanding natural product candidates for the treatment of infectious diseases. The screening practice for phytochemical compound in them is essential to explore more natural sources to replace synthetic antibiotics, which generally have side effects such as hypersensitivity, immune-suppression and allergic reactions. Antibacterial activities have been detected in some of the Malaysian plants and most of the Malaysian medicinal plants have been screened for this property. However, so far no study has focus on Malaysian flowering plants yet. In this study, the extraction and determination of antibacterial property from 19 Malaysian flowering plants were conducted. The plants were extracted with methanol, ethyl acetate, hexane and distilled water, individually at concentration of 0.1g mL-1. The extraction process condition was set to 300 rpm agitation for 10 h at room temperature. The crude extracts of each plant (5 mg/disc) were tested against Bacillus subtilis and Escherichia coli using agar disc diffusion assay method. The screening results showed that ethyl acetate extract of Spathiphyllum cannifolium (‘peace lily’) leaves possesses the highest antibacterial activity against B. subtilis with zone of inhibition of 25 mm. Most of the plant samples extracted with methanol and ethyl acetate have indicated positive activity toward B. subtilis growth. However, the hexane and distilled water extracts was ineffective to combat the B. subtilis growth. Unfortunately, all of the extracts were not active against E. coli. This study suggested that S. cannifolium is highly potential in antibacterial activity which can be further analyzed for the development of new antibiotic exclusively for gram positive bacteria.
format	Article
author	Abdullah, Erlina Ahmad Raus, Raha Jamal, Parveen
author_facet	Abdullah, Erlina Ahmad Raus, Raha Jamal, Parveen
author_sort	Abdullah, Erlina
title	Extraction and evaluation of antibacterial activity from selected flowering plants
title_short	Extraction and evaluation of antibacterial activity from selected flowering plants
title_full	Extraction and evaluation of antibacterial activity from selected flowering plants
title_fullStr	Extraction and evaluation of antibacterial activity from selected flowering plants
title_full_unstemmed	Extraction and evaluation of antibacterial activity from selected flowering plants
title_sort	extraction and evaluation of antibacterial activity from selected flowering plants
publisher	Science Publications
publishDate	2012
url	http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/ http://irep.iium.edu.my/29228/1/Abdullah_et_al_American_Medical_J.pdf
first_indexed	2023-09-18T20:42:53Z
last_indexed	2023-09-18T20:42:53Z
_version_	1777409482771398656

Extraction and evaluation of antibacterial activity from selected flowering plants

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