Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid

Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophace...

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Main Authors:	Abdullah, Hilmi, Mohamad Ismail, Asmahan, Rosman, Azmillah
Format:	Article
Language:	English English
Published:	Malaysian Medical Associations 2012
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf

id	iium-29313
recordtype	eprints
spelling	iium-293132017-09-28T07:18:01Z http://irep.iium.edu.my/29313/ Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah R Medicine (General) Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophaceous gout using febuxostat. The reduction in serum uric acid to target levels was rapid, and the tophi size had also reduced significantly while on therapy. There was no unwanted side effect observed during the therapy. Therefore, febuxostat would be a useful alternative drug in the treatment of hyperuricaemia in gout patients who have contraindications to allopurinol and probenecid Malaysian Medical Associations 2012-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf application/pdf en http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf Abdullah, Hilmi and Mohamad Ismail, Asmahan and Rosman, Azmillah (2012) Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid. Medical Journal of Malaysia, 67 (1). pp. 125-126. ISSN 0300-5283 http://www.myjurnal.my/public/article-view.php?id=58997
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
description	Urate lowering therapy in this country has mainly been achieved by the use of allopurinol and probenecid. A new xanthine oxidase inhibitor called febuxostat has been approved in 2009 for treatment of hyperuricaemia in gout. In this report, we describe the management of a patient with chronic tophaceous gout using febuxostat. The reduction in serum uric acid to target levels was rapid, and the tophi size had also reduced significantly while on therapy. There was no unwanted side effect observed during the therapy. Therefore, febuxostat would be a useful alternative drug in the treatment of hyperuricaemia in gout patients who have contraindications to allopurinol and probenecid
format	Article
author	Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah
author_facet	Abdullah, Hilmi Mohamad Ismail, Asmahan Rosman, Azmillah
author_sort	Abdullah, Hilmi
title	Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
title_short	Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
title_full	Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
title_fullStr	Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
title_full_unstemmed	Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
title_sort	use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid
publisher	Malaysian Medical Associations
publishDate	2012
url	http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/ http://irep.iium.edu.my/29313/1/Use_of_Newly_Available_Febuxostat_in_a_Case_of_Chronic.pdf http://irep.iium.edu.my/29313/4/58485_Use%20of%20newly%20available%20f_scopus.pdf
first_indexed	2023-09-18T20:43:01Z
last_indexed	2023-09-18T20:43:01Z
_version_	1777409491328827392

Use of newly available febuxostat in a case of chronic tophaceous gout contraindicated to allopurinol and probenecid

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