Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations

Background: Primary intracerebral hemorrhage (PICH) remains the deadliest and most disabling form of stroke. The aim of our study was to determine the potential predictors for survival and neurological recovery in PICH patients by clinical-computed tomographic (CT) correlation. Materials and Methods...

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Main Authors:	Rathor, Mohammad Yousuf, Abdul Rani, Mohammed Fauzi, Ab Rahman, Jamalludin, Abdul Rashid, Mohd Amran, Che Abdullah, Shahrin Tarmizi, Mohd Shah, Azarisman Shah
Format:	Article
Language:	English
Published:	Research Department, Isfahan University of Medical Sciences 2012
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/29937/ http://irep.iium.edu.my/29937/ http://irep.iium.edu.my/29937/1/Prediction_of_functional_outcome_in_patients_with.pdf

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spelling	iium-299372016-12-08T01:31:09Z http://irep.iium.edu.my/29937/ Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations Rathor, Mohammad Yousuf Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran Che Abdullah, Shahrin Tarmizi Mohd Shah, Azarisman Shah RC Internal medicine Background: Primary intracerebral hemorrhage (PICH) remains the deadliest and most disabling form of stroke. The aim of our study was to determine the potential predictors for survival and neurological recovery in PICH patients by clinical-computed tomographic (CT) correlation. Materials and Methods: A prospective study conducted among PICH patients at a tertiary care hospital. The clinical and CT scan findings were correlated with the functional outcome using modified Rankin scores (mRS) of 0-5 at discharge and during six months follow-up. Results: The clinical and CT findings in 160 (93 male and 67 female) eligible adult patients with age range from 25 to 85 years (mean age 58.30 ± 11.44 years) were analyzed. The mean Glasgow Coma Scale [GCS] score was significantly higher among survivors. (12.8 ± 0.4 vs. 8.5 ± 0.5, P < 0.001) Based upon the pattern of the CT findings, the best outcome in terms of survival was for the patients with ICH in basal ganglia/internal capsule region (86.7 %), followed by lobar hemorrhage (67.1%). Good functional outcome was associated with a hematoma volume of less than 30 ml. At discharge majority of the survivors were functionally dependent 76 (70.4%) and only 32 (29.6%) achieved functional independence. The significant independent predictors of in- hospital survival were GCS score > 9 (OR 10.8; 95% CI 4.061 to 28.719), basal ganglia/internal capsule bleed (OR 9.750; 95% CI 2.122 to 45.004), hematoma volume <30 ml (OR 11.476; 95% CI 4. 810 to 27.434), no mid line shift (OR 4.901; 95% CI 2.405 to 9.987) and no intraventricular extension of hemorrhage (OR 7.040; 95% CI 3.358 to 14.458). Conclusion: Outcome and functional status at discharge were well correlated with the initial CT scan findings and GCS score. Research Department, Isfahan University of Medical Sciences 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/29937/1/Prediction_of_functional_outcome_in_patients_with.pdf Rathor, Mohammad Yousuf and Abdul Rani, Mohammed Fauzi and Ab Rahman, Jamalludin and Abdul Rashid, Mohd Amran and Che Abdullah, Shahrin Tarmizi and Mohd Shah, Azarisman Shah (2012) Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations. Journal of Research in Medical Sciences, 17 (11). pp. 1056-1062. ISSN 1735-1995 E-ISSN 1735-7136 http://journals.mui.ac.ir/jrms/article/view/8746
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Rathor, Mohammad Yousuf Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran Che Abdullah, Shahrin Tarmizi Mohd Shah, Azarisman Shah Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
description	Background: Primary intracerebral hemorrhage (PICH) remains the deadliest and most disabling form of stroke. The aim of our study was to determine the potential predictors for survival and neurological recovery in PICH patients by clinical-computed tomographic (CT) correlation. Materials and Methods: A prospective study conducted among PICH patients at a tertiary care hospital. The clinical and CT scan findings were correlated with the functional outcome using modified Rankin scores (mRS) of 0-5 at discharge and during six months follow-up. Results: The clinical and CT findings in 160 (93 male and 67 female) eligible adult patients with age range from 25 to 85 years (mean age 58.30 ± 11.44 years) were analyzed. The mean Glasgow Coma Scale [GCS] score was significantly higher among survivors. (12.8 ± 0.4 vs. 8.5 ± 0.5, P < 0.001) Based upon the pattern of the CT findings, the best outcome in terms of survival was for the patients with ICH in basal ganglia/internal capsule region (86.7 %), followed by lobar hemorrhage (67.1%). Good functional outcome was associated with a hematoma volume of less than 30 ml. At discharge majority of the survivors were functionally dependent 76 (70.4%) and only 32 (29.6%) achieved functional independence. The significant independent predictors of in- hospital survival were GCS score > 9 (OR 10.8; 95% CI 4.061 to 28.719), basal ganglia/internal capsule bleed (OR 9.750; 95% CI 2.122 to 45.004), hematoma volume <30 ml (OR 11.476; 95% CI 4. 810 to 27.434), no mid line shift (OR 4.901; 95% CI 2.405 to 9.987) and no intraventricular extension of hemorrhage (OR 7.040; 95% CI 3.358 to 14.458). Conclusion: Outcome and functional status at discharge were well correlated with the initial CT scan findings and GCS score.
format	Article
author	Rathor, Mohammad Yousuf Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran Che Abdullah, Shahrin Tarmizi Mohd Shah, Azarisman Shah
author_facet	Rathor, Mohammad Yousuf Abdul Rani, Mohammed Fauzi Ab Rahman, Jamalludin Abdul Rashid, Mohd Amran Che Abdullah, Shahrin Tarmizi Mohd Shah, Azarisman Shah
author_sort	Rathor, Mohammad Yousuf
title	Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
title_short	Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
title_full	Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
title_fullStr	Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
title_full_unstemmed	Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
title_sort	prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations
publisher	Research Department, Isfahan University of Medical Sciences
publishDate	2012
url	http://irep.iium.edu.my/29937/ http://irep.iium.edu.my/29937/ http://irep.iium.edu.my/29937/1/Prediction_of_functional_outcome_in_patients_with.pdf
first_indexed	2023-09-18T20:43:57Z
last_indexed	2023-09-18T20:43:57Z
_version_	1777409549505921024

Prediction of functional outcome in patients with primary intracerebral hemorrhage by clinical-computed tomographic correlations

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