The effects of noise on cardiovascular parameters using isolated rat`s hearts

Prolonged exposure to noise can have adverse effects on health. Noise has extra auditory effects by activating the sympathetic nervous and hormonal systems. The present study was undertaken to evaluate the effect of acute and chronic high intensity noise on the isolated hearts of rats using the Lang...

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Main Authors: Rahma, Muayad Salm, Win, Ni Ni, H.M, Rafidah, Kamal, Tara, Razali , Ailin
Format: Article
Language:English
Published: Academic Information Press 2012
Subjects:
Online Access:http://irep.iium.edu.my/30102/
http://irep.iium.edu.my/30102/
http://irep.iium.edu.my/30102/1/science-record.pdf
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recordtype eprints
spelling iium-301022014-02-27T01:33:03Z http://irep.iium.edu.my/30102/ The effects of noise on cardiovascular parameters using isolated rat`s hearts Rahma, Muayad Salm Win, Ni Ni H.M, Rafidah Kamal, Tara Razali , Ailin R Medicine (General) Prolonged exposure to noise can have adverse effects on health. Noise has extra auditory effects by activating the sympathetic nervous and hormonal systems. The present study was undertaken to evaluate the effect of acute and chronic high intensity noise on the isolated hearts of rats using the Langendorff apparatus by determining the effect of noise on the coronary perfusion pressure(CPP), heart rate (HR) and left ventricular diastolic pressure (LVDP). The rats were divided into four groups and exposed to noise intensity of 80-100 dBA on duration of 12 hours exposure(acute effect), 8 hours daily for 20 days (chronic effect), 20 days into 3 days exposure and 2 days without 8 hours per day (intermittent effect) and the control group. Noise of 80-100 dBA was found to cause significant increase in CPP, LVDP and HR (p< 0.05) for acute and both chronic groups versus control. On other hand there were no significant differences of the CPP,LVDP and HR between the chronic intermittent group with the chronic continuous noise exposure group. It can be concluded that high intensity noise may have an adverse effect on cardiovascular functions and thus noise exposure should be well monitored. Academic Information Press 2012-12-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/30102/1/science-record.pdf Rahma, Muayad Salm and Win, Ni Ni and H.M, Rafidah and Kamal, Tara and Razali , Ailin (2012) The effects of noise on cardiovascular parameters using isolated rat`s hearts. Science Series Data Report, 4 (12). pp. 39-50. ISSN 1307-119X http://www.researchgate.net/publication/236651807_THE_EFFECTS_OF_NOISE_ON_CARDIOVASCULAR_PARAMETERS_USING_ISOLATEDRAS_HEARTS
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Rahma, Muayad Salm
Win, Ni Ni
H.M, Rafidah
Kamal, Tara
Razali , Ailin
The effects of noise on cardiovascular parameters using isolated rat`s hearts
description Prolonged exposure to noise can have adverse effects on health. Noise has extra auditory effects by activating the sympathetic nervous and hormonal systems. The present study was undertaken to evaluate the effect of acute and chronic high intensity noise on the isolated hearts of rats using the Langendorff apparatus by determining the effect of noise on the coronary perfusion pressure(CPP), heart rate (HR) and left ventricular diastolic pressure (LVDP). The rats were divided into four groups and exposed to noise intensity of 80-100 dBA on duration of 12 hours exposure(acute effect), 8 hours daily for 20 days (chronic effect), 20 days into 3 days exposure and 2 days without 8 hours per day (intermittent effect) and the control group. Noise of 80-100 dBA was found to cause significant increase in CPP, LVDP and HR (p< 0.05) for acute and both chronic groups versus control. On other hand there were no significant differences of the CPP,LVDP and HR between the chronic intermittent group with the chronic continuous noise exposure group. It can be concluded that high intensity noise may have an adverse effect on cardiovascular functions and thus noise exposure should be well monitored.
format Article
author Rahma, Muayad Salm
Win, Ni Ni
H.M, Rafidah
Kamal, Tara
Razali , Ailin
author_facet Rahma, Muayad Salm
Win, Ni Ni
H.M, Rafidah
Kamal, Tara
Razali , Ailin
author_sort Rahma, Muayad Salm
title The effects of noise on cardiovascular parameters using isolated rat`s hearts
title_short The effects of noise on cardiovascular parameters using isolated rat`s hearts
title_full The effects of noise on cardiovascular parameters using isolated rat`s hearts
title_fullStr The effects of noise on cardiovascular parameters using isolated rat`s hearts
title_full_unstemmed The effects of noise on cardiovascular parameters using isolated rat`s hearts
title_sort effects of noise on cardiovascular parameters using isolated rat`s hearts
publisher Academic Information Press
publishDate 2012
url http://irep.iium.edu.my/30102/
http://irep.iium.edu.my/30102/
http://irep.iium.edu.my/30102/1/science-record.pdf
first_indexed 2023-09-18T20:44:12Z
last_indexed 2023-09-18T20:44:12Z
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