Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent
Clerodendrumn viscosum vent. is a majestic and broadly used medicinal plant in Bangladesh and India. This research work was carried out to evaluate the phytochemical and biological activity of Clerodendrum viscosum vent. The powdered barks of the roots were extracted with ethanol by a soxhlet appara...
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INSI Publications
2013
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| Online Access: | http://irep.iium.edu.my/30538/ http://irep.iium.edu.my/30538/ http://irep.iium.edu.my/30538/1/Azad_et_al_AJBAS-IsolationCharacterization_%282%29.pdf |
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iium-305382014-07-21T01:07:30Z http://irep.iium.edu.my/30538/ Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent Abdul Kalam, Azad Wan Sulaiman, Wan Mohd. Azizi Tengku Zakaria, Tengku Muhammad Faris S., Mahmood H. A., Almoustafa Labu, Zubair Khalid QD Chemistry RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine Clerodendrumn viscosum vent. is a majestic and broadly used medicinal plant in Bangladesh and India. This research work was carried out to evaluate the phytochemical and biological activity of Clerodendrum viscosum vent. The powdered barks of the roots were extracted with ethanol by a soxhlet apparatus. Ethanol extract was subjected to TLC (Thin Layer Chromatography) examination. A single spot was observed in n-hexane ethyl acetate (4:1) with Rf values 0.5. Phytochemical screening of the ethanol extract showed the presence of carbohydrates, steroids, tannins, flavonoids, saponines and alkaloids. The crude ethanol extract showed toxic behavior against brine shrimp lethality bioassay. The mortality rate of brine shrimp was found to be increased with the increase in concentration of the sample. From the result on the brine shrimp lethality bioassay it can be well predicted that the crude extracts have considerable cytotoxic potency. INSI Publications 2013-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/30538/1/Azad_et_al_AJBAS-IsolationCharacterization_%282%29.pdf Abdul Kalam, Azad and Wan Sulaiman, Wan Mohd. Azizi and Tengku Zakaria, Tengku Muhammad Faris and S., Mahmood and H. A., Almoustafa and Labu, Zubair Khalid (2013) Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. Australian Journal of Basic and Applied Sciences, 7 (4). pp. 641-647. ISSN 1991-8178 http://ajbasweb.com/old/ajbas/2013/March/641-647.pdf |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
QD Chemistry RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine |
| spellingShingle |
QD Chemistry RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine Abdul Kalam, Azad Wan Sulaiman, Wan Mohd. Azizi Tengku Zakaria, Tengku Muhammad Faris S., Mahmood H. A., Almoustafa Labu, Zubair Khalid Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| description |
Clerodendrumn viscosum vent. is a majestic and broadly used medicinal plant in Bangladesh and India. This research work was carried out to evaluate the phytochemical and biological activity of Clerodendrum viscosum vent. The powdered barks of the roots were extracted with ethanol by a soxhlet apparatus. Ethanol extract was subjected to TLC (Thin Layer Chromatography) examination. A single spot was observed in n-hexane ethyl acetate (4:1) with Rf
values 0.5. Phytochemical screening of the ethanol extract showed the presence of carbohydrates, steroids, tannins, flavonoids, saponines and alkaloids. The crude ethanol extract showed toxic behavior against brine shrimp lethality bioassay. The mortality rate of brine shrimp was found to be increased with the increase in concentration of the sample. From the result on the brine shrimp
lethality bioassay it can be well predicted that the crude extracts have considerable cytotoxic potency. |
| format |
Article |
| author |
Abdul Kalam, Azad Wan Sulaiman, Wan Mohd. Azizi Tengku Zakaria, Tengku Muhammad Faris S., Mahmood H. A., Almoustafa Labu, Zubair Khalid |
| author_facet |
Abdul Kalam, Azad Wan Sulaiman, Wan Mohd. Azizi Tengku Zakaria, Tengku Muhammad Faris S., Mahmood H. A., Almoustafa Labu, Zubair Khalid |
| author_sort |
Abdul Kalam, Azad |
| title |
Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| title_short |
Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| title_full |
Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| title_fullStr |
Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| title_full_unstemmed |
Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| title_sort |
isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent |
| publisher |
INSI Publications |
| publishDate |
2013 |
| url |
http://irep.iium.edu.my/30538/ http://irep.iium.edu.my/30538/ http://irep.iium.edu.my/30538/1/Azad_et_al_AJBAS-IsolationCharacterization_%282%29.pdf |
| first_indexed |
2023-09-18T20:44:43Z |
| last_indexed |
2023-09-18T20:44:43Z |
| _version_ |
1777409597901897728 |