The impact of intrapartum pethidine on the neonatal outcome: a perspective review

Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite...

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Main Authors:	Husin, Roziah, Abdulwahab, Dalia F, BR, Rukaiah, Ismail, Rozihan
Format:	Conference or Workshop Item
Language:	English English
Published:	2012
Subjects:	RG Gynecology and obstetrics
Online Access:	http://irep.iium.edu.my/32077/ http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf

id	iium-32077
recordtype	eprints
spelling	iium-320772013-09-19T08:31:17Z http://irep.iium.edu.my/32077/ The impact of intrapartum pethidine on the neonatal outcome: a perspective review Husin, Roziah Abdulwahab, Dalia F BR, Rukaiah Ismail, Rozihan RG Gynecology and obstetrics Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 minutes (4 hours and 45 minutes). Out of 40 patients, 2 (5%) cases had suspicious CTG 1 hour post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 minutes and one hour respectively. All neonates delivered with good Apgar Score, 8 at 1 minute and 9 at 5 minute. A total of 9 (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery less than 4 hours after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 hours apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome. 2012-06 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf application/pdf en http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf Husin, Roziah and Abdulwahab, Dalia F and BR, Rukaiah and Ismail, Rozihan (2012) The impact of intrapartum pethidine on the neonatal outcome: a perspective review. In: 10th International Scientific Congress of the Royal College of Obstetricians and Gynaecologists, 5-8th June 2012, Kuching, Sarawak.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RG Gynecology and obstetrics
spellingShingle	RG Gynecology and obstetrics Husin, Roziah Abdulwahab, Dalia F BR, Rukaiah Ismail, Rozihan The impact of intrapartum pethidine on the neonatal outcome: a perspective review
description	Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Method: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 minutes (4 hours and 45 minutes). Out of 40 patients, 2 (5%) cases had suspicious CTG 1 hour post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 minutes and one hour respectively. All neonates delivered with good Apgar Score, 8 at 1 minute and 9 at 5 minute. A total of 9 (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery less than 4 hours after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 hours apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome.
format	Conference or Workshop Item
author	Husin, Roziah Abdulwahab, Dalia F BR, Rukaiah Ismail, Rozihan
author_facet	Husin, Roziah Abdulwahab, Dalia F BR, Rukaiah Ismail, Rozihan
author_sort	Husin, Roziah
title	The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_short	The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_full	The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_fullStr	The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_full_unstemmed	The impact of intrapartum pethidine on the neonatal outcome: a perspective review
title_sort	impact of intrapartum pethidine on the neonatal outcome: a perspective review
publishDate	2012
url	http://irep.iium.edu.my/32077/ http://irep.iium.edu.my/32077/2/rcog_pethidine_poster_%281%29.pdf http://irep.iium.edu.my/32077/5/Dear_dr_roziah_%281%29_DrDalia.pdf
first_indexed	2023-09-18T20:46:16Z
last_indexed	2023-09-18T20:46:16Z
_version_	1777409696147177472

The impact of intrapartum pethidine on the neonatal outcome: a perspective review

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