Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia

BACKGROUND AND OBJECTIVES: The role of honey in the treatment of allergic rhinitis (AR) is controversial. We studied the complementary effect of ingestion of a high dose of honey, in addition to standard medications, on AR. DESIGN AND SETTINGS: Prospective randomized placebo-controlled study. Sub...

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Main Authors: Asha'ari, Zamzil Amin, Ahmad, Mohd Zaki, Wan Din, Wan Shah Jihan, Che Hussin, Che Maraina, Leman, Wan Ishlah
Format: Article
Language:English
Published: King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia 2013
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Online Access:http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/1/Honey_improves_AR_symptoms.pdf
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spelling iium-325322014-03-20T01:19:54Z http://irep.iium.edu.my/32532/ Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia Asha'ari, Zamzil Amin Ahmad, Mohd Zaki Wan Din, Wan Shah Jihan Che Hussin, Che Maraina Leman, Wan Ishlah RF Otorhinolaryngology BACKGROUND AND OBJECTIVES: The role of honey in the treatment of allergic rhinitis (AR) is controversial. We studied the complementary effect of ingestion of a high dose of honey, in addition to standard medications, on AR. DESIGN AND SETTINGS: Prospective randomized placebo-controlled study. Subjects were recruited from an otolaryngology clinic in 2 tertiary referral centers in the East coast of Peninsular Malaysia. The study period ranged from April 2010-April 2011. METHODS: Forty AR patients were divided equally into a case group and a control group. All the subjects received a daily dose of 10 mg of loratadine for 4 weeks. The case group ingested 1 g/kg body weight of honey daily in separate doses for the 4-week period. The control group ingested the same dose of honey-flavored corn syrup as placebo. AR symptoms were scored at the start, week 4, and week 8 of the study. RESULTS: There were no significant differences between the mean total symptom score of the case and the control groups at the start of the study. At week 4, both groups showed progressive improvement in the symptoms; at week 8, only the case group showed a continuous improvement in the symptom score. Only the group that ingested honey showed a significant improvement in individual AR symptoms. The improvement persisted for a month after the cessation of the treatment. CONCLUSION: Honey ingestion at a high dose improves the overall and individual symptoms of AR, and it could serve as a complementary therapy for AR. King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia 2013-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32532/1/Honey_improves_AR_symptoms.pdf Asha'ari, Zamzil Amin and Ahmad, Mohd Zaki and Wan Din, Wan Shah Jihan and Che Hussin, Che Maraina and Leman, Wan Ishlah (2013) Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia. Annals of Saudi Medicine, 33 (5). pp. 469-475. ISSN 0256-4947 http://www.annsaudimed.net/index.php/about_journal.html 10.5144/0256-4947.2013.469
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RF Otorhinolaryngology
spellingShingle RF Otorhinolaryngology
Asha'ari, Zamzil Amin
Ahmad, Mohd Zaki
Wan Din, Wan Shah Jihan
Che Hussin, Che Maraina
Leman, Wan Ishlah
Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
description BACKGROUND AND OBJECTIVES: The role of honey in the treatment of allergic rhinitis (AR) is controversial. We studied the complementary effect of ingestion of a high dose of honey, in addition to standard medications, on AR. DESIGN AND SETTINGS: Prospective randomized placebo-controlled study. Subjects were recruited from an otolaryngology clinic in 2 tertiary referral centers in the East coast of Peninsular Malaysia. The study period ranged from April 2010-April 2011. METHODS: Forty AR patients were divided equally into a case group and a control group. All the subjects received a daily dose of 10 mg of loratadine for 4 weeks. The case group ingested 1 g/kg body weight of honey daily in separate doses for the 4-week period. The control group ingested the same dose of honey-flavored corn syrup as placebo. AR symptoms were scored at the start, week 4, and week 8 of the study. RESULTS: There were no significant differences between the mean total symptom score of the case and the control groups at the start of the study. At week 4, both groups showed progressive improvement in the symptoms; at week 8, only the case group showed a continuous improvement in the symptom score. Only the group that ingested honey showed a significant improvement in individual AR symptoms. The improvement persisted for a month after the cessation of the treatment. CONCLUSION: Honey ingestion at a high dose improves the overall and individual symptoms of AR, and it could serve as a complementary therapy for AR.
format Article
author Asha'ari, Zamzil Amin
Ahmad, Mohd Zaki
Wan Din, Wan Shah Jihan
Che Hussin, Che Maraina
Leman, Wan Ishlah
author_facet Asha'ari, Zamzil Amin
Ahmad, Mohd Zaki
Wan Din, Wan Shah Jihan
Che Hussin, Che Maraina
Leman, Wan Ishlah
author_sort Asha'ari, Zamzil Amin
title Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
title_short Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
title_full Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
title_fullStr Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
title_full_unstemmed Ingestion of honey improves the symptoms of allergic rhinitis: Evidence from a randomized placebo-controlled trial in the East Coast of Peninsular Malaysia
title_sort ingestion of honey improves the symptoms of allergic rhinitis: evidence from a randomized placebo-controlled trial in the east coast of peninsular malaysia
publisher King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
publishDate 2013
url http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/
http://irep.iium.edu.my/32532/1/Honey_improves_AR_symptoms.pdf
first_indexed 2023-09-18T20:46:56Z
last_indexed 2023-09-18T20:46:56Z
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