Plants’ metabolites as potential antiobesity agents

Obesity and obesity-related complications are on the increase both in the developed and developing world. Since existing pharmaceuticals fail to come up with long-term solutions to address this issue, there is an ever-pressing need to find and develop new drugs and alternatives. Natural products, pa...

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Main Authors:	Sahib, Najla Gooda, Saari, Nazamid, Ismail, Amin, Khatib, Alfi, Mahomoodally, Fawzi, Abdul Hamid, Azizah
Format:	Article
Language:	English
Published:	The ScientificWorld Journal 2012
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/1/Shabib_et_al._2012.pdf

id	iium-33296
recordtype	eprints
spelling	iium-332962013-12-13T07:59:13Z http://irep.iium.edu.my/33296/ Plants’ metabolites as potential antiobesity agents Sahib, Najla Gooda Saari, Nazamid Ismail, Amin Khatib, Alfi Mahomoodally, Fawzi Abdul Hamid, Azizah QD Chemistry Obesity and obesity-related complications are on the increase both in the developed and developing world. Since existing pharmaceuticals fail to come up with long-term solutions to address this issue, there is an ever-pressing need to find and develop new drugs and alternatives. Natural products, particularly medicinal plants, are believed to harbor potential antiobesity agents that can act through various mechanisms either by preventing weight gain or promoting weight loss amongst others. The inhibition of key lipid and carbohydrate hydrolyzing and metabolizing enzymes, disruption of adipogenesis, and modulation of its factors or appetite suppression are some of the plethora of targeted approaches to probe the antiobesity potential of medicinal plants. A new technology such as metabolomics, which deals with the study of the whole metabolome, has been identified to be a promising technique to probe the progression of diseases, elucidate their pathologies, and assess the effects of natural health products on certain pathological conditions. This has been applied to drug research, bone health, and to a limited extent to obesity research. This paper thus endeavors to give an overview of those plants, which have been reported to have antiobesity effects and highlight the potential and relevance of metabolomics in obesity research. The ScientificWorld Journal 2012-03-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/33296/1/Shabib_et_al._2012.pdf Sahib, Najla Gooda and Saari, Nazamid and Ismail, Amin and Khatib, Alfi and Mahomoodally, Fawzi and Abdul Hamid, Azizah (2012) Plants’ metabolites as potential antiobesity agents. The ScientificWorld Journal, 436039. pp. 1-8. ISSN 1537-744X http://www.hindawi.com/journals/tswj/2012/436039/ 10.1100/2012/436039
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Sahib, Najla Gooda Saari, Nazamid Ismail, Amin Khatib, Alfi Mahomoodally, Fawzi Abdul Hamid, Azizah Plants’ metabolites as potential antiobesity agents
description	Obesity and obesity-related complications are on the increase both in the developed and developing world. Since existing pharmaceuticals fail to come up with long-term solutions to address this issue, there is an ever-pressing need to find and develop new drugs and alternatives. Natural products, particularly medicinal plants, are believed to harbor potential antiobesity agents that can act through various mechanisms either by preventing weight gain or promoting weight loss amongst others. The inhibition of key lipid and carbohydrate hydrolyzing and metabolizing enzymes, disruption of adipogenesis, and modulation of its factors or appetite suppression are some of the plethora of targeted approaches to probe the antiobesity potential of medicinal plants. A new technology such as metabolomics, which deals with the study of the whole metabolome, has been identified to be a promising technique to probe the progression of diseases, elucidate their pathologies, and assess the effects of natural health products on certain pathological conditions. This has been applied to drug research, bone health, and to a limited extent to obesity research. This paper thus endeavors to give an overview of those plants, which have been reported to have antiobesity effects and highlight the potential and relevance of metabolomics in obesity research.
format	Article
author	Sahib, Najla Gooda Saari, Nazamid Ismail, Amin Khatib, Alfi Mahomoodally, Fawzi Abdul Hamid, Azizah
author_facet	Sahib, Najla Gooda Saari, Nazamid Ismail, Amin Khatib, Alfi Mahomoodally, Fawzi Abdul Hamid, Azizah
author_sort	Sahib, Najla Gooda
title	Plants’ metabolites as potential antiobesity agents
title_short	Plants’ metabolites as potential antiobesity agents
title_full	Plants’ metabolites as potential antiobesity agents
title_fullStr	Plants’ metabolites as potential antiobesity agents
title_full_unstemmed	Plants’ metabolites as potential antiobesity agents
title_sort	plants’ metabolites as potential antiobesity agents
publisher	The ScientificWorld Journal
publishDate	2012
url	http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/ http://irep.iium.edu.my/33296/1/Shabib_et_al._2012.pdf
first_indexed	2023-09-18T20:48:07Z
last_indexed	2023-09-18T20:48:07Z
_version_	1777409812418527232

Plants’ metabolites as potential antiobesity agents

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