Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic

Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic

Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high...

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Main Authors: Omar , Ahmad Marzuki, Abd Rahim, Firdaus, Sukor, Norlela, Shahar, Mohammad Arif, Kamaruddin, Nor Azmi
Format: Article
Language:English
Published: Malaysian Endocrine and Metabolic Society 2013
Subjects:
R Medicine (General)
RC Internal medicine
Online Access:http://irep.iium.edu.my/33553/
http://irep.iium.edu.my/33553/
http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf
id iium-33553
recordtype eprints
spelling iium-335532014-07-22T04:23:49Z http://irep.iium.edu.my/33553/ Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic Omar , Ahmad Marzuki Abd Rahim, Firdaus Sukor, Norlela Shahar, Mohammad Arif Kamaruddin, Nor Azmi R Medicine (General) RC Internal medicine Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high plasma aldosterone concentration (PAC) (>150 pg/mL) in hypertensive subjects attending a primary care clinic. Methods: This was a cross-sectional study involving 220 essential hypertension subjects from a primary care clinic in Kuala Lumpur. Bloods for aldosterone, renin and renal profile were taken as specified in previously published protocols. Results: The prevalence of positive test for PA was 7.3%. When either ARR>20 or PAC >150 pg/mL were used, 15.0% and 17.7% of subjects fulfilled the criteria, respectively. Conclusions: The prevalence of hypertensive subjects with high ARR (>20) and PAC (>150 pg/mL) was 7.3%, justifying the need to investigate this group of subjects for PA. Malaysian Endocrine and Metabolic Society 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf Omar , Ahmad Marzuki and Abd Rahim, Firdaus and Sukor, Norlela and Shahar, Mohammad Arif and Kamaruddin, Nor Azmi (2013) Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic. Journal of Endocrinology and Metabolism, 3 (1). pp. 40-47. ISSN 2229-9572 http://www.jmems.org/index.php/jmems/article/viewFile/76/60
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
RC Internal medicine
spellingShingle R Medicine (General)
RC Internal medicine
Omar , Ahmad Marzuki
Abd Rahim, Firdaus
Sukor, Norlela
Shahar, Mohammad Arif
Kamaruddin, Nor Azmi
Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
description Screening test by using aldosterone-renin ratio (ARR) resulted in a higher prevalence (5-15%) of primary aldosteronism than was previously expected but to date there is no such study performed in Malaysia. Objectives: The aim of the study was to determine the prevalence of high ARR (>20) and high plasma aldosterone concentration (PAC) (>150 pg/mL) in hypertensive subjects attending a primary care clinic. Methods: This was a cross-sectional study involving 220 essential hypertension subjects from a primary care clinic in Kuala Lumpur. Bloods for aldosterone, renin and renal profile were taken as specified in previously published protocols. Results: The prevalence of positive test for PA was 7.3%. When either ARR>20 or PAC >150 pg/mL were used, 15.0% and 17.7% of subjects fulfilled the criteria, respectively. Conclusions: The prevalence of hypertensive subjects with high ARR (>20) and PAC (>150 pg/mL) was 7.3%, justifying the need to investigate this group of subjects for PA.
format Article
author Omar , Ahmad Marzuki
Abd Rahim, Firdaus
Sukor, Norlela
Shahar, Mohammad Arif
Kamaruddin, Nor Azmi
author_facet Omar , Ahmad Marzuki
Abd Rahim, Firdaus
Sukor, Norlela
Shahar, Mohammad Arif
Kamaruddin, Nor Azmi
author_sort Omar , Ahmad Marzuki
title Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
title_short Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
title_full Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
title_fullStr Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
title_full_unstemmed Prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
title_sort prevalence of high aldosterone-renin ratio and plasma aldosterone levels among hypertensive patients at a primary care clinic
publisher Malaysian Endocrine and Metabolic Society
publishDate 2013
url http://irep.iium.edu.my/33553/
http://irep.iium.edu.my/33553/
http://irep.iium.edu.my/33553/1/76-267-1-PB.pdf
first_indexed 2023-09-18T20:48:30Z
last_indexed 2023-09-18T20:48:30Z
_version_ 1777409836255805440

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