Anti-inflammatory activities of Cinnomomum burmanni Bl

Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipxygenase (SLO) and hyaluronidase (HAse). C. burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing highest SLO inhi...

Full description

Bibliographic Details
Main Authors:	Khatib, Alfi, Mi-Yeon, Kim, Shin-Kyo, Chung
Format:	Article
Language:	English
Published:	The Korean Society of Food Science and Technology 2005
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/1/Khatib_et_al%2C_2005.pdf

id	iium-33756
recordtype	eprints
spelling	iium-337562013-12-30T03:41:03Z http://irep.iium.edu.my/33756/ Anti-inflammatory activities of Cinnomomum burmanni Bl Khatib, Alfi Mi-Yeon, Kim Shin-Kyo, Chung QD Chemistry Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipxygenase (SLO) and hyaluronidase (HAse). C. burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing highest SLO inhibitory activity was isolated using silica gel-60 column chromatography. Two compounds were isolated and purified through preparative HPLC. Through analysis of UV, 1H-NMR, 13-C NMR, EI-MS and FAB+-MS, compounds 1 and 2 were identified as coumarin and 2-hydroxy cinnamaldehyde, respectively, among which 2-hydroxy cinnamaldehyde showed SLO inhibitory activity of IC50=60mikroM. Both compounds did not exhibit HAse inhibitory activity. The Korean Society of Food Science and Technology 2005-05-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/33756/1/Khatib_et_al%2C_2005.pdf Khatib, Alfi and Mi-Yeon, Kim and Shin-Kyo, Chung (2005) Anti-inflammatory activities of Cinnomomum burmanni Bl. Food Science and Biotechnology, 14 (2). pp. 223-227. ISSN 2092-6456 (O), 1226-7708 (P) http://link.springer.com/journal/10068
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Khatib, Alfi Mi-Yeon, Kim Shin-Kyo, Chung Anti-inflammatory activities of Cinnomomum burmanni Bl
description	Anti-inflammatory assay was conducted on 20 kinds of traditional Indonesian medicinal herbs using soybean lipxygenase (SLO) and hyaluronidase (HAse). C. burmanni Bl showed highest anti-inflammatory activity. Ethyl acetate fraction from methanol extract of C. burmanni Bl bark showing highest SLO inhibitory activity was isolated using silica gel-60 column chromatography. Two compounds were isolated and purified through preparative HPLC. Through analysis of UV, 1H-NMR, 13-C NMR, EI-MS and FAB+-MS, compounds 1 and 2 were identified as coumarin and 2-hydroxy cinnamaldehyde, respectively, among which 2-hydroxy cinnamaldehyde showed SLO inhibitory activity of IC50=60mikroM. Both compounds did not exhibit HAse inhibitory activity.
format	Article
author	Khatib, Alfi Mi-Yeon, Kim Shin-Kyo, Chung
author_facet	Khatib, Alfi Mi-Yeon, Kim Shin-Kyo, Chung
author_sort	Khatib, Alfi
title	Anti-inflammatory activities of Cinnomomum burmanni Bl
title_short	Anti-inflammatory activities of Cinnomomum burmanni Bl
title_full	Anti-inflammatory activities of Cinnomomum burmanni Bl
title_fullStr	Anti-inflammatory activities of Cinnomomum burmanni Bl
title_full_unstemmed	Anti-inflammatory activities of Cinnomomum burmanni Bl
title_sort	anti-inflammatory activities of cinnomomum burmanni bl
publisher	The Korean Society of Food Science and Technology
publishDate	2005
url	http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/ http://irep.iium.edu.my/33756/1/Khatib_et_al%2C_2005.pdf
first_indexed	2023-09-18T20:48:49Z
last_indexed	2023-09-18T20:48:49Z
_version_	1777409856480739328

Anti-inflammatory activities of Cinnomomum burmanni Bl

Similar Items