Homology modeling of Pyranose 2-Oxidase from Phanerochaete Chrysosporium
Currently, most of the demands for energy relied on petroleum products. Nevertheless, the issues of energy security, economics and environment has led to the breakthrough of biofuel cells (BFCs) technology as one of the promising solution to the problems. However, the performance of BFCs need to...
| Main Authors: | , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English English |
| Published: |
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/34145/ http://irep.iium.edu.my/34145/3/ICBIOE_2013_Cover_Page_till_Table_of_contents.pdf http://irep.iium.edu.my/34145/9/Homology_P2Ox_-_ICBioE2013_proceedings_pp590-593.pdf |
| Summary: | Currently, most of the demands for energy relied on petroleum products. Nevertheless, the issues of
energy security, economics and environment has led to the breakthrough of biofuel cells (BFCs)
technology as one of the promising solution to the problems. However, the performance of BFCs
need to be improved in order to compete with the existing technologies. One way to improve the
efficiency of BFCs is to ensure that the enzyme used as the catalyst in BFCs, in this case, pyranose
2-oxidase (P2Ox) has better binding characteristic and broad substrate specificity. For this purpose,
studies on three-dimensional (3-D) structure of P2Ox enzyme can offer insights on the structurefunction
correlations. Unfortunately, at present there is no available crystal structure of P2Ox from
P. chrysosporium (PcP2Ox). Thus, in this study homology modelling was used as the reliable
alternative method to predict the 3-D structure of PcP2Ox enzyme. The structural information
obtained here can provide necessary information to model and design more efficient PcP2Ox.
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