Survival of lung cancer patients in a resource-limited country

Aim: Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. Method: All patients diagnosed with lung cancer from August 2007 to August 2010 were...

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Main Authors:	How, Soon Hin, Ng, Teck Han, Kuan, Yeh Chunn, Ab Rahman, Jamalludin, Fauzi, Abdul Rani
Format:	Article
Language:	English English English
Published:	John Wiley & Sons 2015
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/3/lung_cancer_acceptance_e_mail.jpeg http://irep.iium.edu.my/34285/7/Lung_cancer_AJCO.pdf http://irep.iium.edu.my/34285/10/Surviva_of_lung_cancer_patients.pdf

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recordtype	eprints
spelling	iium-342852016-03-11T09:09:50Z http://irep.iium.edu.my/34285/ Survival of lung cancer patients in a resource-limited country How, Soon Hin Ng, Teck Han Kuan, Yeh Chunn Ab Rahman, Jamalludin Fauzi, Abdul Rani R Medicine (General) Aim: Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. Method: All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single referral hospital of the state of Pahang, Malaysia. Detailed demographic data, ECOG (Eastern Cooperation Oncology Group) performance status, stage of disease and treatment were recorded. The date of histology or cytology confirmation was used as the date of entry. Survival time was calculated from the date of entry to the date of death. Results: One hundred forty-nine patients were included for survival analysis. The median age was 62 years and patients were predominantly males (78%) and smokers (78%). The majority had non-small cell lung cancer (NSCLC) (94%); only six patients (4%) had small cell lung cancer. All patients presented with stage 3 or stage 4 disease. Overall median survival was 18 weeks. “No definitive treatment” and “ECOG 3–4” were the significant independent predictors of death, with the hazard ratios of 2.1 (95% confidence interval [CI] 1.4, 3.0) and 1.6 (95% CI 1.1, 2.3) times, respectively. Among NSCLC patients on treatment, 1- and 2-year survival rates were 27% and 15%, respectively. Conclusion: The majority of lung cancer patients in Pahang presented with advanced disease. No definitive treatment and ECOG 3–4 were independent poor prognostic factors. John Wiley & Sons 2015-09-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/34285/3/lung_cancer_acceptance_e_mail.jpeg application/pdf en http://irep.iium.edu.my/34285/7/Lung_cancer_AJCO.pdf application/pdf en http://irep.iium.edu.my/34285/10/Surviva_of_lung_cancer_patients.pdf How, Soon Hin and Ng, Teck Han and Kuan, Yeh Chunn and Ab Rahman, Jamalludin and Fauzi, Abdul Rani (2015) Survival of lung cancer patients in a resource-limited country. Asia-Pacific Journal of Clinical Oncology, 11 (3). pp. 221-227. ISSN 1743-7563 http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291743-7563 10.1111/ajco.12179
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) How, Soon Hin Ng, Teck Han Kuan, Yeh Chunn Ab Rahman, Jamalludin Fauzi, Abdul Rani Survival of lung cancer patients in a resource-limited country
description	Aim: Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. Method: All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single referral hospital of the state of Pahang, Malaysia. Detailed demographic data, ECOG (Eastern Cooperation Oncology Group) performance status, stage of disease and treatment were recorded. The date of histology or cytology confirmation was used as the date of entry. Survival time was calculated from the date of entry to the date of death. Results: One hundred forty-nine patients were included for survival analysis. The median age was 62 years and patients were predominantly males (78%) and smokers (78%). The majority had non-small cell lung cancer (NSCLC) (94%); only six patients (4%) had small cell lung cancer. All patients presented with stage 3 or stage 4 disease. Overall median survival was 18 weeks. “No definitive treatment” and “ECOG 3–4” were the significant independent predictors of death, with the hazard ratios of 2.1 (95% confidence interval [CI] 1.4, 3.0) and 1.6 (95% CI 1.1, 2.3) times, respectively. Among NSCLC patients on treatment, 1- and 2-year survival rates were 27% and 15%, respectively. Conclusion: The majority of lung cancer patients in Pahang presented with advanced disease. No definitive treatment and ECOG 3–4 were independent poor prognostic factors.
format	Article
author	How, Soon Hin Ng, Teck Han Kuan, Yeh Chunn Ab Rahman, Jamalludin Fauzi, Abdul Rani
author_facet	How, Soon Hin Ng, Teck Han Kuan, Yeh Chunn Ab Rahman, Jamalludin Fauzi, Abdul Rani
author_sort	How, Soon Hin
title	Survival of lung cancer patients in a resource-limited country
title_short	Survival of lung cancer patients in a resource-limited country
title_full	Survival of lung cancer patients in a resource-limited country
title_fullStr	Survival of lung cancer patients in a resource-limited country
title_full_unstemmed	Survival of lung cancer patients in a resource-limited country
title_sort	survival of lung cancer patients in a resource-limited country
publisher	John Wiley & Sons
publishDate	2015
url	http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/ http://irep.iium.edu.my/34285/3/lung_cancer_acceptance_e_mail.jpeg http://irep.iium.edu.my/34285/7/Lung_cancer_AJCO.pdf http://irep.iium.edu.my/34285/10/Surviva_of_lung_cancer_patients.pdf
first_indexed	2023-09-18T20:49:27Z
last_indexed	2023-09-18T20:49:27Z
_version_	1777409895785562112

Survival of lung cancer patients in a resource-limited country

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