Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh

The study was aimed to evaluate the pharmaceutical properties of few selected generic products of ranitidine hydrochloride tablets available in retail pharmacies of Bangladesh. We collected 10 nationally manufactured generic ranitidine HCl tablets from local Market who followed USP specifications...

Full description

Bibliographic Details
Main Authors:	Islam, Mohd Aminul, Azad, Abul Kalam, Mohd Azizi, Wan
Format:	Article
Language:	English
Published:	ANSI 2013
Subjects:	RA0421 Public health. Hygiene. Preventive Medicine
Online Access:	http://irep.iium.edu.my/35264/ http://irep.iium.edu.my/35264/ http://irep.iium.edu.my/35264/1/PJN_2688.pdf

id	iium-35264
recordtype	eprints
spelling	iium-352642014-02-04T06:13:41Z http://irep.iium.edu.my/35264/ Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh Islam, Mohd Aminul Azad, Abul Kalam Mohd Azizi, Wan RA0421 Public health. Hygiene. Preventive Medicine The study was aimed to evaluate the pharmaceutical properties of few selected generic products of ranitidine hydrochloride tablets available in retail pharmacies of Bangladesh. We collected 10 nationally manufactured generic ranitidine HCl tablets from local Market who followed USP specifications and examined their physical parameters and potency to check their compliance with the USP. The intention was to evaluate the quality of this pharmaceuticals after 20 years of implementing the National Drug Policy in 1982. All tested ranitidine tablet samples (Rt1-Rt10) were selectively collected from local retail pharmacies in Savar, Dhaka-1344, Bangladesh. Before purchasing the samples, their physical appearance, name of manufacturer, batch number, date of manufacturing, expiry date, manufacturing license number and Maximum Retail Price (MRP) were properly checked. The various parameters of the selected samples such as diameter, shape, size, weight variation, thickness, hardness, disintegration, dissolution and potency have been determined according to the American Pharmacopoeia USP 27 requirements. It was found that all ten selected products met the USP 27 specifications. The differences in hardness among the tablets were significant. Interestingly, dissolution profiles of some tablet products were not weighty different from one another, whereas those of tablets were significantly different. However, all brands complied with USP 27. It could be concluded that the selected ranitidine HCl tablets met the required USP specifications and are considered quality products in terms of the mentioned parameters. ANSI 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/35264/1/PJN_2688.pdf Islam, Mohd Aminul and Azad, Abul Kalam and Mohd Azizi, Wan (2013) Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh. Pakistan Journal of Nutrition, 12 (11). pp. 966-972. ISSN 1680-5194 http://www.pjbs.org/pjnonline/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RA0421 Public health. Hygiene. Preventive Medicine
spellingShingle	RA0421 Public health. Hygiene. Preventive Medicine Islam, Mohd Aminul Azad, Abul Kalam Mohd Azizi, Wan Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
description	The study was aimed to evaluate the pharmaceutical properties of few selected generic products of ranitidine hydrochloride tablets available in retail pharmacies of Bangladesh. We collected 10 nationally manufactured generic ranitidine HCl tablets from local Market who followed USP specifications and examined their physical parameters and potency to check their compliance with the USP. The intention was to evaluate the quality of this pharmaceuticals after 20 years of implementing the National Drug Policy in 1982. All tested ranitidine tablet samples (Rt1-Rt10) were selectively collected from local retail pharmacies in Savar, Dhaka-1344, Bangladesh. Before purchasing the samples, their physical appearance, name of manufacturer, batch number, date of manufacturing, expiry date, manufacturing license number and Maximum Retail Price (MRP) were properly checked. The various parameters of the selected samples such as diameter, shape, size, weight variation, thickness, hardness, disintegration, dissolution and potency have been determined according to the American Pharmacopoeia USP 27 requirements. It was found that all ten selected products met the USP 27 specifications. The differences in hardness among the tablets were significant. Interestingly, dissolution profiles of some tablet products were not weighty different from one another, whereas those of tablets were significantly different. However, all brands complied with USP 27. It could be concluded that the selected ranitidine HCl tablets met the required USP specifications and are considered quality products in terms of the mentioned parameters.
format	Article
author	Islam, Mohd Aminul Azad, Abul Kalam Mohd Azizi, Wan
author_facet	Islam, Mohd Aminul Azad, Abul Kalam Mohd Azizi, Wan
author_sort	Islam, Mohd Aminul
title	Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
title_short	Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
title_full	Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
title_fullStr	Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
title_full_unstemmed	Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh
title_sort	appraisement of ranitidine hydrochloride tablet (usp150mg) preparations from few selected companies in bangladesh
publisher	ANSI
publishDate	2013
url	http://irep.iium.edu.my/35264/ http://irep.iium.edu.my/35264/ http://irep.iium.edu.my/35264/1/PJN_2688.pdf
first_indexed	2023-09-18T20:50:36Z
last_indexed	2023-09-18T20:50:36Z
_version_	1777409967892987904

Appraisement of Ranitidine Hydrochloride Tablet (USP150mg) Preparations from Few Selected Companies in Bangladesh

Similar Items