The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice

Red tilapia (Oreochromis niloticus) is one of aquaculture’s most adaptive species. It is abundantly found in the wild and known to be cultured in several parts of the world. It is mainly a freshwater fish, inhabiting shallow streams, ponds, rivers and lakes but less commonly found living in brackish...

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Main Authors:	Abdul Rahman, Suzanah, Zambry, Husna, Basha, Sadak, Kamarzaman, Saheera, Khan Chowdhury, Ahmed Jalal
Format:	Article
Language:	English
Published:	Journal of Applied Pharmaceutical Science (http://www.japsonline.com) 2013
Subjects:	QH301 Biology QP Physiology R Medicine (General)
Online Access:	http://irep.iium.edu.my/35723/ http://irep.iium.edu.my/35723/ http://irep.iium.edu.my/35723/1/Red_Tilapia_Suzanah.pdf

id	iium-35723
recordtype	eprints
spelling	iium-357232017-12-06T05:16:09Z http://irep.iium.edu.my/35723/ The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice Abdul Rahman, Suzanah Zambry, Husna Basha, Sadak Kamarzaman, Saheera Khan Chowdhury, Ahmed Jalal QH301 Biology QP Physiology R Medicine (General) Red tilapia (Oreochromis niloticus) is one of aquaculture’s most adaptive species. It is abundantly found in the wild and known to be cultured in several parts of the world. It is mainly a freshwater fish, inhabiting shallow streams, ponds, rivers and lakes but less commonly found living in brackish water. The concept of ‘waste to wealth’ has been applied widely as an alternative to waste reduction and environmental conservation. Based on these perspectives, the present study was conducted to assess possible medicinal and pharmaceutical values of the tilapia. The mice model of delayed-contact hypersensitivity test, the mice ear swelling test (MEST), was chosen for this study due to its ability to predict contact sensitization with less cost and time consumed. Four female BALB/c mice were tested in each group which included controls. Three different doses of scales powder at 500, 1000, and 2000 mg/kg in an acetone and olive oil (AOO) solution were formulated and applied to shaved dorsal trunk of the mice at induction phase, and to both sides of each ear of the mice at elicitation phase. From the observations made throughout the study period, neither erythema nor oedema was formed on the skin of mice treated with scales powder in AOO solution. Mice ear thickness increase showed percentage ear swelling of no more than 20%. Thus, the finding of this study showed that the scales of red tilapia fish did not induce allergic sensitization and could have an application in medicinal and pharmaceutical industries. Journal of Applied Pharmaceutical Science (http://www.japsonline.com) 2013-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/35723/1/Red_Tilapia_Suzanah.pdf Abdul Rahman, Suzanah and Zambry, Husna and Basha, Sadak and Kamarzaman, Saheera and Khan Chowdhury, Ahmed Jalal (2013) The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice. Journal of Applied Pharmaceutical Science, 3 (10). pp. 45-50. ISSN 2231-3354 http://www.japsonline.com/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QH301 Biology QP Physiology R Medicine (General)
spellingShingle	QH301 Biology QP Physiology R Medicine (General) Abdul Rahman, Suzanah Zambry, Husna Basha, Sadak Kamarzaman, Saheera Khan Chowdhury, Ahmed Jalal The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
description	Red tilapia (Oreochromis niloticus) is one of aquaculture’s most adaptive species. It is abundantly found in the wild and known to be cultured in several parts of the world. It is mainly a freshwater fish, inhabiting shallow streams, ponds, rivers and lakes but less commonly found living in brackish water. The concept of ‘waste to wealth’ has been applied widely as an alternative to waste reduction and environmental conservation. Based on these perspectives, the present study was conducted to assess possible medicinal and pharmaceutical values of the tilapia. The mice model of delayed-contact hypersensitivity test, the mice ear swelling test (MEST), was chosen for this study due to its ability to predict contact sensitization with less cost and time consumed. Four female BALB/c mice were tested in each group which included controls. Three different doses of scales powder at 500, 1000, and 2000 mg/kg in an acetone and olive oil (AOO) solution were formulated and applied to shaved dorsal trunk of the mice at induction phase, and to both sides of each ear of the mice at elicitation phase. From the observations made throughout the study period, neither erythema nor oedema was formed on the skin of mice treated with scales powder in AOO solution. Mice ear thickness increase showed percentage ear swelling of no more than 20%. Thus, the finding of this study showed that the scales of red tilapia fish did not induce allergic sensitization and could have an application in medicinal and pharmaceutical industries.
format	Article
author	Abdul Rahman, Suzanah Zambry, Husna Basha, Sadak Kamarzaman, Saheera Khan Chowdhury, Ahmed Jalal
author_facet	Abdul Rahman, Suzanah Zambry, Husna Basha, Sadak Kamarzaman, Saheera Khan Chowdhury, Ahmed Jalal
author_sort	Abdul Rahman, Suzanah
title	The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
title_short	The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
title_full	The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
title_fullStr	The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
title_full_unstemmed	The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice
title_sort	potential role of red tilapia (oreochromis niloticus) scales: allergic reaction test in mice
publisher	Journal of Applied Pharmaceutical Science (http://www.japsonline.com)
publishDate	2013
url	http://irep.iium.edu.my/35723/ http://irep.iium.edu.my/35723/ http://irep.iium.edu.my/35723/1/Red_Tilapia_Suzanah.pdf
first_indexed	2023-09-18T20:51:11Z
last_indexed	2023-09-18T20:51:11Z
_version_	1777410004936032256

The potential role of Red Tilapia (Oreochromis niloticus) scales: allergic reaction test in mice

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