In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff

Alpinia galanga and Alpinia conchigera are belongs to the Zingiberaceae family, distributed in Asia and particularly in the Southeast Asia. The rhizomes of A. galanga have been extensively used as condiment for flavoring and local medicines for the stomach ache, carminative and treating diarrhea. In...

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Main Authors:	Khan, Farman Ullah, Md. Jaffri, Juliana, Bakhtiar, M. Taher
Format:	Conference or Workshop Item
Language:	English
Published:	2013
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/36158/ http://irep.iium.edu.my/36158/ http://irep.iium.edu.my/36158/1/Binder1.pdf

id	iium-36158
recordtype	eprints
spelling	iium-361582014-04-16T00:50:59Z http://irep.iium.edu.my/36158/ In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff Khan, Farman Ullah Md. Jaffri, Juliana Bakhtiar, M. Taher RS Pharmacy and materia medica Alpinia galanga and Alpinia conchigera are belongs to the Zingiberaceae family, distributed in Asia and particularly in the Southeast Asia. The rhizomes of A. galanga have been extensively used as condiment for flavoring and local medicines for the stomach ache, carminative and treating diarrhea. In traditional medicine A. conchigera has been used to treat illnesses such as muscle pain and to stop bleeding. The aims of this study to evaluate the antifungal and antibacterial activities of A. galanga and A. canchigera on several strains of microbes including those which are associated with skin infection. To determine the antibacterial and antifungal activities of A. galanga and A. conchigera, disc diffusion method was used. The antibacterial and antifungal activities of hexane, dichloromethane and methanolic extracts of A. galanga and A. conchigera have been evaluated against gram positive and gram negative bacteria including multi-drug resistant Staphylococcus aureus (MRSA) and fungi such as Trichophyton rubrum, Microsporum canis and Candida albicans, using daptomycin, streptomycin and nystatin as standards respectively. The hexane and methanol extracts showed significant antibacterial and antifungal activities with the zone of inhibition ranging from 14-26 mm, while MRSA was the most susceptible to the hexane extract of A. conchigera. The MIC of both plant A. galanga and A. conchigera were found 35.61 and 30.5 ug/mL respectively against MRSA. 2013-03 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/36158/1/Binder1.pdf Khan, Farman Ullah and Md. Jaffri, Juliana and Bakhtiar, M. Taher (2013) In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff. In: International Conference on Natural Products 2014, 18th-19th March 2014, Palm Garden Hotel, IOI Resorts, Putrajaya, Malaysia. http://www.ukm.my/icnp2014/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Khan, Farman Ullah Md. Jaffri, Juliana Bakhtiar, M. Taher In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
description	Alpinia galanga and Alpinia conchigera are belongs to the Zingiberaceae family, distributed in Asia and particularly in the Southeast Asia. The rhizomes of A. galanga have been extensively used as condiment for flavoring and local medicines for the stomach ache, carminative and treating diarrhea. In traditional medicine A. conchigera has been used to treat illnesses such as muscle pain and to stop bleeding. The aims of this study to evaluate the antifungal and antibacterial activities of A. galanga and A. canchigera on several strains of microbes including those which are associated with skin infection. To determine the antibacterial and antifungal activities of A. galanga and A. conchigera, disc diffusion method was used. The antibacterial and antifungal activities of hexane, dichloromethane and methanolic extracts of A. galanga and A. conchigera have been evaluated against gram positive and gram negative bacteria including multi-drug resistant Staphylococcus aureus (MRSA) and fungi such as Trichophyton rubrum, Microsporum canis and Candida albicans, using daptomycin, streptomycin and nystatin as standards respectively. The hexane and methanol extracts showed significant antibacterial and antifungal activities with the zone of inhibition ranging from 14-26 mm, while MRSA was the most susceptible to the hexane extract of A. conchigera. The MIC of both plant A. galanga and A. conchigera were found 35.61 and 30.5 ug/mL respectively against MRSA.
format	Conference or Workshop Item
author	Khan, Farman Ullah Md. Jaffri, Juliana Bakhtiar, M. Taher
author_facet	Khan, Farman Ullah Md. Jaffri, Juliana Bakhtiar, M. Taher
author_sort	Khan, Farman Ullah
title	In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
title_short	In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
title_full	In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
title_fullStr	In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
title_full_unstemmed	In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff
title_sort	in-vitro antifungal and antibacterial activities of rhizomes extracts of alpinia galanga and alpinia conchigera griff
publishDate	2013
url	http://irep.iium.edu.my/36158/ http://irep.iium.edu.my/36158/ http://irep.iium.edu.my/36158/1/Binder1.pdf
first_indexed	2023-09-18T20:51:46Z
last_indexed	2023-09-18T20:51:46Z
_version_	1777410041525043200

In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff

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