Antimicrobial studies of cosmos caudatus kunth. (Compositae)

The present study aims to investigate crude n-hexane, diethyl ether (Et2O), ethanol (EtOH) and phosphate buffered saline (PBS) extracts of Cosmos caudatus Kunth leaves for their antimicrobial potential against 5 microbial strains comprising 2 Gram positive bacteria: Bacillus subtilis, Staphylococcu...

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Main Authors: Md Rasdi, Nor Hafipah, Abd. Samah, Othman, Sule, Abubakar, Ahmed, Qamar Uddin
Format: Article
Language:English
Published: Academic Journals 2010
Subjects:
Online Access:http://irep.iium.edu.my/3630/
http://irep.iium.edu.my/3630/
http://irep.iium.edu.my/3630/1/Rasdi_et_al.pdf
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recordtype eprints
spelling iium-36302012-05-06T06:32:54Z http://irep.iium.edu.my/3630/ Antimicrobial studies of cosmos caudatus kunth. (Compositae) Md Rasdi, Nor Hafipah Abd. Samah, Othman Sule, Abubakar Ahmed, Qamar Uddin Q Science (General) The present study aims to investigate crude n-hexane, diethyl ether (Et2O), ethanol (EtOH) and phosphate buffered saline (PBS) extracts of Cosmos caudatus Kunth leaves for their antimicrobial potential against 5 microbial strains comprising 2 Gram positive bacteria: Bacillus subtilis, Staphylococcus aureus, 2 Gram negative bacteria: Escherichia coli, Pseudomonas aeruginosa and 1 fungi: Candida albicans by the disc diffusion method. Preliminary antimicrobial screening showed inhibition by the n-hexane, diethyl ether, and ethanol extracts against all the tested microbes, however the phosphate buffered saline extract was inactive against Bacillus subtilis and Staphylococcus aureus. MIC values ranging from 6.25 - 25 mg/ml for the tested crude extracts were obtained by the microtiter plate method. This study showed that the crude extracts of the leaves of C. caudatus Kunth. could be potential source of new antimicrobial agents especially to treat infections caused by the tested microbial strains and confirms its utility in folk medicines. Academic Journals 2010-04-18 Article PeerReviewed application/pdf en http://irep.iium.edu.my/3630/1/Rasdi_et_al.pdf Md Rasdi, Nor Hafipah and Abd. Samah, Othman and Sule, Abubakar and Ahmed, Qamar Uddin (2010) Antimicrobial studies of cosmos caudatus kunth. (Compositae). Journal of Medicinal Plants Research, 4 (8). pp. 669-673. ISSN 1996-0875 http://www.academicjournals.org/jmpr/abstracts/abstracts/abstracts2010/18Apr/Rasdi%20et%20al.htm
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Md Rasdi, Nor Hafipah
Abd. Samah, Othman
Sule, Abubakar
Ahmed, Qamar Uddin
Antimicrobial studies of cosmos caudatus kunth. (Compositae)
description The present study aims to investigate crude n-hexane, diethyl ether (Et2O), ethanol (EtOH) and phosphate buffered saline (PBS) extracts of Cosmos caudatus Kunth leaves for their antimicrobial potential against 5 microbial strains comprising 2 Gram positive bacteria: Bacillus subtilis, Staphylococcus aureus, 2 Gram negative bacteria: Escherichia coli, Pseudomonas aeruginosa and 1 fungi: Candida albicans by the disc diffusion method. Preliminary antimicrobial screening showed inhibition by the n-hexane, diethyl ether, and ethanol extracts against all the tested microbes, however the phosphate buffered saline extract was inactive against Bacillus subtilis and Staphylococcus aureus. MIC values ranging from 6.25 - 25 mg/ml for the tested crude extracts were obtained by the microtiter plate method. This study showed that the crude extracts of the leaves of C. caudatus Kunth. could be potential source of new antimicrobial agents especially to treat infections caused by the tested microbial strains and confirms its utility in folk medicines.
format Article
author Md Rasdi, Nor Hafipah
Abd. Samah, Othman
Sule, Abubakar
Ahmed, Qamar Uddin
author_facet Md Rasdi, Nor Hafipah
Abd. Samah, Othman
Sule, Abubakar
Ahmed, Qamar Uddin
author_sort Md Rasdi, Nor Hafipah
title Antimicrobial studies of cosmos caudatus kunth. (Compositae)
title_short Antimicrobial studies of cosmos caudatus kunth. (Compositae)
title_full Antimicrobial studies of cosmos caudatus kunth. (Compositae)
title_fullStr Antimicrobial studies of cosmos caudatus kunth. (Compositae)
title_full_unstemmed Antimicrobial studies of cosmos caudatus kunth. (Compositae)
title_sort antimicrobial studies of cosmos caudatus kunth. (compositae)
publisher Academic Journals
publishDate 2010
url http://irep.iium.edu.my/3630/
http://irep.iium.edu.my/3630/
http://irep.iium.edu.my/3630/1/Rasdi_et_al.pdf
first_indexed 2023-09-18T20:11:31Z
last_indexed 2023-09-18T20:11:31Z
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