Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours

Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megapros...

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Main Authors:	Wan Ismail, Wan Mohd Faisham, Sharifudin, Mohd Ariff, Wan , Zulmi, Halim, Ahmad Sukari, Mat Zin, Nor Azman, Wan Sulaiman, Wan Azman
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
Online Access:	http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf

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spelling	iium-363372018-06-20T01:00:46Z http://irep.iium.edu.my/36337/ Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megaprosthesis at our centre for the past 15 years. Results: Nine patients were included in our review. Mean age of patients was 21.3 years (range 12 to 35 years old). Seven had osteosarcoma of the femur and two were results of salvage procedure for implant loosening following distal femoral replacement. Another patient underwent surgery for revision of total femur allograft. Free oncologic margins were achieved in all patients. Four patients required vascularised latissimus dorsi free flaps cover for reconstruction of soft tissue defects. The average follow-up was 137 months, ranging from 24 to 180 months. Seven patients were still alive on their last follow up. Six of them being disease free and one survived with presence of pulmonary and contralateral femur metastases. Two patients were complicated with infections, two had stiff knee joint, and one case of peroneal nerve palsy. Excellent or good functional outcomes obtained in all patients on their last follow up in accordance to Musculoskeletal Tumor Society (MSTS) Scoring System. Conclusion: Modular endoprosthetic replacement is a good reconstruction option in selected cases. It provides early stability and good functional outcomes. However, it is a technically demanding procedure. 2014-04 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf application/pdf en http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf Wan Ismail, Wan Mohd Faisham and Sharifudin, Mohd Ariff and Wan , Zulmi and Halim, Ahmad Sukari and Mat Zin, Nor Azman and Wan Sulaiman, Wan Azman (2014) Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours. In: 10th Annual Asia Pacific Musculoskeletal Tumour Society (APMSTS) Scientific Meeting, 9-11 Apr 2014, Grand Hyatt Melbourne Australia. http://apmsts2014.aoa.org.au/program/4568385151
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics
spellingShingle	RB Pathology RC0254 Neoplasms. Tumors. Oncology (including Cancer) RD701 Orthopedics Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
description	Introduction: Total femur endoprosthesis is an alternative reconstruction option following resection for massive malignant bone tumour with intramedullary extension or skip lesions. Methodology: We reviewed cases with primary bone tumours underwent total femur resection and replacement with megaprosthesis at our centre for the past 15 years. Results: Nine patients were included in our review. Mean age of patients was 21.3 years (range 12 to 35 years old). Seven had osteosarcoma of the femur and two were results of salvage procedure for implant loosening following distal femoral replacement. Another patient underwent surgery for revision of total femur allograft. Free oncologic margins were achieved in all patients. Four patients required vascularised latissimus dorsi free flaps cover for reconstruction of soft tissue defects. The average follow-up was 137 months, ranging from 24 to 180 months. Seven patients were still alive on their last follow up. Six of them being disease free and one survived with presence of pulmonary and contralateral femur metastases. Two patients were complicated with infections, two had stiff knee joint, and one case of peroneal nerve palsy. Excellent or good functional outcomes obtained in all patients on their last follow up in accordance to Musculoskeletal Tumor Society (MSTS) Scoring System. Conclusion: Modular endoprosthetic replacement is a good reconstruction option in selected cases. It provides early stability and good functional outcomes. However, it is a technically demanding procedure.
format	Conference or Workshop Item
author	Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman
author_facet	Wan Ismail, Wan Mohd Faisham Sharifudin, Mohd Ariff Wan , Zulmi Halim, Ahmad Sukari Mat Zin, Nor Azman Wan Sulaiman, Wan Azman
author_sort	Wan Ismail, Wan Mohd Faisham
title	Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
title_short	Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
title_full	Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
title_fullStr	Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
title_full_unstemmed	Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
title_sort	outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours
publishDate	2014
url	http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/ http://irep.iium.edu.my/36337/1/TOTAL_FEMUR_%28APMSTS_2014%29.pdf http://irep.iium.edu.my/36337/2/APMSTS_2014_-_PROGRAMME_%26_ABSTRACT_BOOK_-_Paper_Presentations.pdf
first_indexed	2023-09-18T20:52:02Z
last_indexed	2023-09-18T20:52:02Z
_version_	1777410058768875520

Outcomes following total femur resection and modular endoprosthetic replacement for primary bone tumours

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