Chemical characterization and antioxidant activity of three medicinal Apiaceae species

tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differ...

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Main Authors:	., Maulidiani, Abas, Faridah, Khatib, Alfi, Shaari, Khozirah
Format:	Article
Language:	English English
Published:	Elsevier 2014
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf

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spelling	iium-363832017-09-19T08:27:59Z http://irep.iium.edu.my/36383/ Chemical characterization and antioxidant activity of three medicinal Apiaceae species ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah QD Chemistry tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differentPegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabo-lite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-typetriterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotylespecies consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due tothe difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evalu-ated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, andxanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potentantioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 mikrog/ml; XOI = 87.68 mikrog/ml) as compared toH. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 mikrog/ml; XOI = 32.23 mikrog/ml) and H. sibthorpioides(TPC = 56.23 mg/100 g DW; DPPH = 37.86 mikrog/ml; XOI = 14.73. mikrog/ml). Elsevier 2014-03-15 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf application/pdf en http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf ., Maulidiani and Abas, Faridah and Khatib, Alfi and Shaari, Khozirah (2014) Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Industrial Crops and Products, 55. pp. 238-247. ISSN 0926-6690 http://www.sciencedirect.com/science/article/pii/S0926669014000910# 10.1016/j.indcrop.2014.02.013
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry ., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah Chemical characterization and antioxidant activity of three medicinal Apiaceae species
description	tCentella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredientsin pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and elec-trospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differentPegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabo-lite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-typetriterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotylespecies consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due tothe difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evalu-ated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, andxanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potentantioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 mikrog/ml; XOI = 87.68 mikrog/ml) as compared toH. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 mikrog/ml; XOI = 32.23 mikrog/ml) and H. sibthorpioides(TPC = 56.23 mg/100 g DW; DPPH = 37.86 mikrog/ml; XOI = 14.73. mikrog/ml).
format	Article
author	., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah
author_facet	., Maulidiani Abas, Faridah Khatib, Alfi Shaari, Khozirah
author_sort	., Maulidiani
title	Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_short	Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_full	Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_fullStr	Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_full_unstemmed	Chemical characterization and antioxidant activity of three medicinal Apiaceae species
title_sort	chemical characterization and antioxidant activity of three medicinal apiaceae species
publisher	Elsevier
publishDate	2014
url	http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/ http://irep.iium.edu.my/36383/1/Maulidiani_et_al._2014.pdf http://irep.iium.edu.my/36383/4/36383_Chemical%20characterization%20and%20antioxidant_SCOPUS.pdf
first_indexed	2023-09-18T20:52:07Z
last_indexed	2023-09-18T20:52:07Z
_version_	1777410063944646656

Chemical characterization and antioxidant activity of three medicinal Apiaceae species

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