Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model

Hyperlipidemia, a metabolic disorder closely associated with the modern life-style and eating habits, is increasingly prevalent among the world population. This study was conducted on obese rats to evaluate the efficacy of Cosmos caudatus leaves as a treatment of hyperlipidemia. Hyperlipidemic condi...

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Main Authors:	Perumal, Vikneswari, A. Hamid, Azizah, Ismail, Amin, Saari, Khozirah, Abas, Faridah, Ismail, Intan S., Maulidiani, Lajis, Nordin. H., Khatib, Alfi
Format:	Article
Language:	English
Published:	ESci Journals Publishing 2014
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/36603/ http://irep.iium.edu.my/36603/ http://irep.iium.edu.my/36603/1/450-4102-2-PB.pdf

id	iium-36603
recordtype	eprints
spelling	iium-366032018-06-20T07:00:01Z http://irep.iium.edu.my/36603/ Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model Perumal, Vikneswari A. Hamid, Azizah Ismail, Amin Saari, Khozirah Abas, Faridah Ismail, Intan S. Maulidiani, Lajis, Nordin. H. Khatib, Alfi QD Chemistry Hyperlipidemia, a metabolic disorder closely associated with the modern life-style and eating habits, is increasingly prevalent among the world population. This study was conducted on obese rats to evaluate the efficacy of Cosmos caudatus leaves as a treatment of hyperlipidemia. Hyperlipidemic conditions were induced in rats by submitting them to a high-fat diet during 3 months. After this, the rats were administered 200 mg/kg body weight of an ethanolic C. caudatus leaf extract or 35 mg/kg body weight atorvastatin for four weeks. The rats treated with the C. caudatus extract showed a significant (P<0.05) reduction of plasma triglycerides, total cholesterol, low density lipoprotein-cholesterol and glucose, and a significant (P< 0.05) increase in high density lipoprotein-cholesterol and Atherogenic Index values. The study indicated that supplementation with C. caudatus has a potential for the treatment of hyperlipidemia. ESci Journals Publishing 2014-03-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/36603/1/450-4102-2-PB.pdf Perumal, Vikneswari and A. Hamid, Azizah and Ismail, Amin and Saari, Khozirah and Abas, Faridah and Ismail, Intan S. and Maulidiani, and Lajis, Nordin. H. and Khatib, Alfi (2014) Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model. Journal of Food Chemistry and Nutrition, 2 (1). pp. 43-51. ISSN 2307-4124 (O), 2308-7943 (P) http://www.escijournals.net/index.php/JFCN/article/view/450#.U3LbyaJrEgc
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Perumal, Vikneswari A. Hamid, Azizah Ismail, Amin Saari, Khozirah Abas, Faridah Ismail, Intan S. Maulidiani, Lajis, Nordin. H. Khatib, Alfi Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
description	Hyperlipidemia, a metabolic disorder closely associated with the modern life-style and eating habits, is increasingly prevalent among the world population. This study was conducted on obese rats to evaluate the efficacy of Cosmos caudatus leaves as a treatment of hyperlipidemia. Hyperlipidemic conditions were induced in rats by submitting them to a high-fat diet during 3 months. After this, the rats were administered 200 mg/kg body weight of an ethanolic C. caudatus leaf extract or 35 mg/kg body weight atorvastatin for four weeks. The rats treated with the C. caudatus extract showed a significant (P<0.05) reduction of plasma triglycerides, total cholesterol, low density lipoprotein-cholesterol and glucose, and a significant (P< 0.05) increase in high density lipoprotein-cholesterol and Atherogenic Index values. The study indicated that supplementation with C. caudatus has a potential for the treatment of hyperlipidemia.
format	Article
author	Perumal, Vikneswari A. Hamid, Azizah Ismail, Amin Saari, Khozirah Abas, Faridah Ismail, Intan S. Maulidiani, Lajis, Nordin. H. Khatib, Alfi
author_facet	Perumal, Vikneswari A. Hamid, Azizah Ismail, Amin Saari, Khozirah Abas, Faridah Ismail, Intan S. Maulidiani, Lajis, Nordin. H. Khatib, Alfi
author_sort	Perumal, Vikneswari
title	Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
title_short	Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
title_full	Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
title_fullStr	Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
title_full_unstemmed	Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
title_sort	effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model
publisher	ESci Journals Publishing
publishDate	2014
url	http://irep.iium.edu.my/36603/ http://irep.iium.edu.my/36603/ http://irep.iium.edu.my/36603/1/450-4102-2-PB.pdf
first_indexed	2023-09-18T20:52:26Z
last_indexed	2023-09-18T20:52:26Z
_version_	1777410083239493632

Effect of cosmos caudatus kunth leaves on the lipid profile of a hyperlipidemia-induced animal model

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