Mathematical verification of summary formula in retinal vessel diameter measurement
our previous study found the retinal vessel diameter measurement using summary formula has no significant difference for the multiple retinal images of the same person, while the individual vessel measures show the significant difference. It was speculated that the revised formula summariz...
| Main Authors: | , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/36995/ http://irep.iium.edu.my/36995/ http://irep.iium.edu.my/36995/ http://irep.iium.edu.my/36995/1/HaoBRC2013_MathsVerification.pdf |
| Summary: | our previous study found the retinal vessel
diameter measurement using summary formula has
no significant difference for the multiple retinal
images of the same person, while the individual vessel
measures show the significant difference. It was
speculated that the revised formula summarizing the
individual measures and therefore against variation.
This paper uses the mathematical models to verify
this speculation. The impacts of the sample size,
branching coefficients, different graders and
grader/systemic errors are analyzed and discussed.
Our results confirmed the revised formula is robust
against the variation which exists on the individual
measures. However, the results also demonstrate 1)
the revised formula is not able to remove the systemic
errors and the variations caused by the different
graders. 2) the measures summarized by the revised
formula may not be suitable for monitoring the
changes on the individual retinal vessels.
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