Subchondral bone plate thickening precedes chondrocyte apoptosis and cartilage degradation in spontaneous animal models of osteoarthritis

Subchondral bone plate thickening precedes chondrocyte apoptosis and cartilage degradation in spontaneous animal models of osteoarthritis

Osteoarthritis (OA) is the most common joint disorder characterised by bone remodelling and cartilage degradation and associated with chondrocyte apoptosis. These processes were investigated at 10, 16, 24, and 30 weeks in Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs that develop OA spo...

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Bibliographic Details
Main Authors: Zamli, Zaitunnatakhin, Brown, Kate Robson, Tarlton, John F., Adams, Mike A., Torlot, Georgina E., Cartwright, Charlie, Cook, William A., Vassilevskaja, Kristiina, Sharif, Mohammed
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2014
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/37057/
http://irep.iium.edu.my/37057/
http://irep.iium.edu.my/37057/
http://irep.iium.edu.my/37057/1/Subchondral_Bone_Plate_Thickening_Precedes_Chondrocyte_Apoptosis_and_Cartilage_Degradation_in_Spontaneous_Animal_Models_of_Osteoarthritis.pdf

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