Estimating the survival times of HIV patients using a markov chain

In this paper, real-world data are used to estimate CDC (Center for Disease Control) stage transition times for patients diagnosed with HIV using statistical methods. The method that will be used for these estimations will be an analysis of a finite state Markov chain. For the purposes of this thesi...

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Main Authors: Crews, Trenton, Khamis, Imad, Daoud, Jamal Ibrahim
Format: Article
Language:English
Published: INSI Publications 2011
Subjects:
Online Access:http://irep.iium.edu.my/3730/
http://irep.iium.edu.my/3730/
http://irep.iium.edu.my/3730/1/Jamal-10.pdf
id iium-3730
recordtype eprints
spelling iium-37302011-12-23T09:02:14Z http://irep.iium.edu.my/3730/ Estimating the survival times of HIV patients using a markov chain Crews, Trenton Khamis, Imad Daoud, Jamal Ibrahim HA Statistics In this paper, real-world data are used to estimate CDC (Center for Disease Control) stage transition times for patients diagnosed with HIV using statistical methods. The method that will be used for these estimations will be an analysis of a finite state Markov chain. For the purposes of this thesis, two populations will be analyzed. The two populations are men and women. A one-step transition matrix will be derived for both of the populations. Using this one-step transition matrix, a steady-state probability vector will also be derived. The data and the corresponding results will then be used to make a comparison between the two populations. The data were collected by observing individuals infected with HIV. Individuals who were active in the study were observed every six months. During these observations, each individual’s CDC stage was recorded. Involvement in the study was voluntary resulting in many individuals only being observed once which meant that no data concerning their transition from one CDC stage to another could be acquired. Even with the large number of individuals who discontinued their participation in the study, there were still a large number of individuals who maintained their participation throughout the duration of the study and ensured that the variance and error estimates of the results would be negligible. INSI Publications 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/3730/1/Jamal-10.pdf Crews, Trenton and Khamis, Imad and Daoud, Jamal Ibrahim (2011) Estimating the survival times of HIV patients using a markov chain. Australian Journal of Basic and Applied Sciences, 5 (5). pp. 41-48. ISSN 1991-8178 http://www.insipub.com/online.html
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic HA Statistics
spellingShingle HA Statistics
Crews, Trenton
Khamis, Imad
Daoud, Jamal Ibrahim
Estimating the survival times of HIV patients using a markov chain
description In this paper, real-world data are used to estimate CDC (Center for Disease Control) stage transition times for patients diagnosed with HIV using statistical methods. The method that will be used for these estimations will be an analysis of a finite state Markov chain. For the purposes of this thesis, two populations will be analyzed. The two populations are men and women. A one-step transition matrix will be derived for both of the populations. Using this one-step transition matrix, a steady-state probability vector will also be derived. The data and the corresponding results will then be used to make a comparison between the two populations. The data were collected by observing individuals infected with HIV. Individuals who were active in the study were observed every six months. During these observations, each individual’s CDC stage was recorded. Involvement in the study was voluntary resulting in many individuals only being observed once which meant that no data concerning their transition from one CDC stage to another could be acquired. Even with the large number of individuals who discontinued their participation in the study, there were still a large number of individuals who maintained their participation throughout the duration of the study and ensured that the variance and error estimates of the results would be negligible.
format Article
author Crews, Trenton
Khamis, Imad
Daoud, Jamal Ibrahim
author_facet Crews, Trenton
Khamis, Imad
Daoud, Jamal Ibrahim
author_sort Crews, Trenton
title Estimating the survival times of HIV patients using a markov chain
title_short Estimating the survival times of HIV patients using a markov chain
title_full Estimating the survival times of HIV patients using a markov chain
title_fullStr Estimating the survival times of HIV patients using a markov chain
title_full_unstemmed Estimating the survival times of HIV patients using a markov chain
title_sort estimating the survival times of hiv patients using a markov chain
publisher INSI Publications
publishDate 2011
url http://irep.iium.edu.my/3730/
http://irep.iium.edu.my/3730/
http://irep.iium.edu.my/3730/1/Jamal-10.pdf
first_indexed 2023-09-18T20:11:40Z
last_indexed 2023-09-18T20:11:40Z
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