Induced mass change technique for glucose detection in microcantilever-based sensors

Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes...

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Main Authors:	Mohd Nor, Mardhiah, Bais, Badariah, Abd Aziz, Norazreen, Ab Rahim, Rosminazuin, Yeop Majlis, Burhanuddin
Format:	Conference or Workshop Item
Language:	English
Published:	2012
Subjects:	T Technology (General)
Online Access:	http://irep.iium.edu.my/38797/ http://irep.iium.edu.my/38797/ http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf

id	iium-38797
recordtype	eprints
spelling	iium-387972014-10-16T03:05:52Z http://irep.iium.edu.my/38797/ Induced mass change technique for glucose detection in microcantilever-based sensors Mohd Nor, Mardhiah Bais, Badariah Abd Aziz, Norazreen Ab Rahim, Rosminazuin Yeop Majlis, Burhanuddin T Technology (General) Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes due to the glucose reaction. The induced force is then used to test the fabricated microcantilever sensor for glucose detection. Gold-coated glass slides were used as the immobilization sites for glucose oxidase enzyme. The reaction of the glucose oxidase enzyme and ß-D glucose was observed by injecting 5 mM glucose solution on 0.3 mL immobilized enzyme on three samples. The resulted mass changes, ranging from 151.87 mg to 180. 14 mg for the three samples, indicate a good correlation between the enzyme-glucose reaction and the induced mass change. The induced forces of 0.28 μN to 0.29 μN, converted from the mass changes of the glucose-enzyme reaction, is in a range of interactive force values commonly found in biochemical detection applications. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf Mohd Nor, Mardhiah and Bais, Badariah and Abd Aziz, Norazreen and Ab Rahim, Rosminazuin and Yeop Majlis, Burhanuddin (2012) Induced mass change technique for glucose detection in microcantilever-based sensors. In: 10th IEEE International Conference on Semiconductor Electronics, ICSE 2012, 19-21 September 2012, Kuala Lumpur, Malaysia. http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6417155&tag=1
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	T Technology (General)
spellingShingle	T Technology (General) Mohd Nor, Mardhiah Bais, Badariah Abd Aziz, Norazreen Ab Rahim, Rosminazuin Yeop Majlis, Burhanuddin Induced mass change technique for glucose detection in microcantilever-based sensors
description	Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes due to the glucose reaction. The induced force is then used to test the fabricated microcantilever sensor for glucose detection. Gold-coated glass slides were used as the immobilization sites for glucose oxidase enzyme. The reaction of the glucose oxidase enzyme and ß-D glucose was observed by injecting 5 mM glucose solution on 0.3 mL immobilized enzyme on three samples. The resulted mass changes, ranging from 151.87 mg to 180. 14 mg for the three samples, indicate a good correlation between the enzyme-glucose reaction and the induced mass change. The induced forces of 0.28 μN to 0.29 μN, converted from the mass changes of the glucose-enzyme reaction, is in a range of interactive force values commonly found in biochemical detection applications.
format	Conference or Workshop Item
author	Mohd Nor, Mardhiah Bais, Badariah Abd Aziz, Norazreen Ab Rahim, Rosminazuin Yeop Majlis, Burhanuddin
author_facet	Mohd Nor, Mardhiah Bais, Badariah Abd Aziz, Norazreen Ab Rahim, Rosminazuin Yeop Majlis, Burhanuddin
author_sort	Mohd Nor, Mardhiah
title	Induced mass change technique for glucose detection in microcantilever-based sensors
title_short	Induced mass change technique for glucose detection in microcantilever-based sensors
title_full	Induced mass change technique for glucose detection in microcantilever-based sensors
title_fullStr	Induced mass change technique for glucose detection in microcantilever-based sensors
title_full_unstemmed	Induced mass change technique for glucose detection in microcantilever-based sensors
title_sort	induced mass change technique for glucose detection in microcantilever-based sensors
publishDate	2012
url	http://irep.iium.edu.my/38797/ http://irep.iium.edu.my/38797/ http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf
first_indexed	2023-09-18T20:55:45Z
last_indexed	2023-09-18T20:55:45Z
_version_	1777410292180844544

Induced mass change technique for glucose detection in microcantilever-based sensors

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