Particle formation and micronization using non-conventional techniques- review

Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 '...

Full description

Bibliographic Details
Main Authors:	Karim, Fahim Tamzeedul, Sarker, Md. Zaidul Islam, Abu Bakar, Mohd Rushdi, U.M., Salim, Awang, Mohamed, Ferdosh, Sahena, Khan Chowdhury, Ahmed Jalal, Sharif, K. M., Hossain, Md Sohrab
Format:	Article
Language:	English English
Published:	Elsevier B.V 2014
Subjects:	Q Science (General) T Technology (General)
Online Access:	http://irep.iium.edu.my/38952/ http://irep.iium.edu.my/38952/ http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf

id	iium-38952
recordtype	eprints
spelling	iium-389522019-10-09T08:20:14Z http://irep.iium.edu.my/38952/ Particle formation and micronization using non-conventional techniques- review Karim, Fahim Tamzeedul Sarker, Md. Zaidul Islam Abu Bakar, Mohd Rushdi U.M., Salim Awang, Mohamed Ferdosh, Sahena Khan Chowdhury, Ahmed Jalal Sharif, K. M. Hossain, Md Sohrab Q Science (General) T Technology (General) Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 'C, P > 7.3 MPa) has been used in food and pharmaceutical industries to minimize the use of organic solvents, produce new food products, produce environmentally superior food products and to process and micronize (0.1–5mm) pharmaceuticals. Control of particle size increases the dissolution rate of drugs into the body. Techniques that use sc CO2 eliminate inherent drawbacks of conventional methods such as thermal or mechanical degradation of the product, poor control of the particle size and morphology, lack of brittleness of some polymers and low encapsulation efficiency. Severaltechniques have been reported for the particle formation and micronization using supercritical fluids that have been successfully scaled up for commercial use. Supercritical CO2 has also been used to develop applications for medicines, essential oils, vitamins, food grade polymers, catalysts and pigments. This review highlights the process mechanism of supercritical fluid based techniques as well as some applications on particle formation and micronization. Elsevier B.V 2014-10-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf application/pdf en http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf Karim, Fahim Tamzeedul and Sarker, Md. Zaidul Islam and Abu Bakar, Mohd Rushdi and U.M., Salim and Awang, Mohamed and Ferdosh, Sahena and Khan Chowdhury, Ahmed Jalal and Sharif, K. M. and Hossain, Md Sohrab (2014) Particle formation and micronization using non-conventional techniques- review. Chemical Engineering and Processing: Process Intensification, 86 (2014). pp. 47-52. ISSN 0255-2701 http://www.journals.elsevier.com/chemical-engineering-and-processing-process-intensification/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General) T Technology (General)
spellingShingle	Q Science (General) T Technology (General) Karim, Fahim Tamzeedul Sarker, Md. Zaidul Islam Abu Bakar, Mohd Rushdi U.M., Salim Awang, Mohamed Ferdosh, Sahena Khan Chowdhury, Ahmed Jalal Sharif, K. M. Hossain, Md Sohrab Particle formation and micronization using non-conventional techniques- review
description	Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 'C, P > 7.3 MPa) has been used in food and pharmaceutical industries to minimize the use of organic solvents, produce new food products, produce environmentally superior food products and to process and micronize (0.1–5mm) pharmaceuticals. Control of particle size increases the dissolution rate of drugs into the body. Techniques that use sc CO2 eliminate inherent drawbacks of conventional methods such as thermal or mechanical degradation of the product, poor control of the particle size and morphology, lack of brittleness of some polymers and low encapsulation efficiency. Severaltechniques have been reported for the particle formation and micronization using supercritical fluids that have been successfully scaled up for commercial use. Supercritical CO2 has also been used to develop applications for medicines, essential oils, vitamins, food grade polymers, catalysts and pigments. This review highlights the process mechanism of supercritical fluid based techniques as well as some applications on particle formation and micronization.
format	Article
author	Karim, Fahim Tamzeedul Sarker, Md. Zaidul Islam Abu Bakar, Mohd Rushdi U.M., Salim Awang, Mohamed Ferdosh, Sahena Khan Chowdhury, Ahmed Jalal Sharif, K. M. Hossain, Md Sohrab
author_facet	Karim, Fahim Tamzeedul Sarker, Md. Zaidul Islam Abu Bakar, Mohd Rushdi U.M., Salim Awang, Mohamed Ferdosh, Sahena Khan Chowdhury, Ahmed Jalal Sharif, K. M. Hossain, Md Sohrab
author_sort	Karim, Fahim Tamzeedul
title	Particle formation and micronization using non-conventional techniques- review
title_short	Particle formation and micronization using non-conventional techniques- review
title_full	Particle formation and micronization using non-conventional techniques- review
title_fullStr	Particle formation and micronization using non-conventional techniques- review
title_full_unstemmed	Particle formation and micronization using non-conventional techniques- review
title_sort	particle formation and micronization using non-conventional techniques- review
publisher	Elsevier B.V
publishDate	2014
url	http://irep.iium.edu.my/38952/ http://irep.iium.edu.my/38952/ http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf
first_indexed	2023-09-18T20:55:58Z
last_indexed	2023-09-18T20:55:58Z
_version_	1777410305758855168

Particle formation and micronization using non-conventional techniques- review

Similar Items