Kesan in vitro rilmenidine ke atas rembesan insulin

This study was carried out to determine the in vitro effect of a new antihypertensive drug, Rilmenidine, on insulin secretion. The direct effect of Rilmenidine on glucose-induced insulin secretion was studied using isolated rat pancreas. The concentrations of Rilmenidine used were based on the peak...

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Main Authors:	Hashim, Rosnani, Abdul Razak, Tariq, Hashim, Suhaimi
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2003
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/400/ http://irep.iium.edu.my/400/ http://irep.iium.edu.my/400/1/Jurnal_Sains_Kesihatan_Malaysia_Jilid_I_2003.pdf

id	iium-400
recordtype	eprints
spelling	iium-4002011-08-08T00:44:35Z http://irep.iium.edu.my/400/ Kesan in vitro rilmenidine ke atas rembesan insulin Hashim, Rosnani Abdul Razak, Tariq Hashim, Suhaimi RM Therapeutics. Pharmacology This study was carried out to determine the in vitro effect of a new antihypertensive drug, Rilmenidine, on insulin secretion. The direct effect of Rilmenidine on glucose-induced insulin secretion was studied using isolated rat pancreas. The concentrations of Rilmenidine used were based on the peak plasma concentration achieved with an oral dose of 1 mg. T a low concentration, Rilmenidine (0.35 ng/ml) significantly stimulated insulin secretion (p‹0.01). However, Rilmenidine showed a significantly weak inhibition (p< 0.05) at 3.5 ng/ml and a strong inhibitin at a higher concentration (35.0 ng/ml). The result showed that Rilmenidine exhibited significant stimulating and inhibitory effects on insulin secretion from the pancreas at different concentrations. Penerbit Universiti Kebangsaan Malaysia 2003 Article PeerReviewed application/pdf en http://irep.iium.edu.my/400/1/Jurnal_Sains_Kesihatan_Malaysia_Jilid_I_2003.pdf Hashim, Rosnani and Abdul Razak, Tariq and Hashim, Suhaimi (2003) Kesan in vitro rilmenidine ke atas rembesan insulin. Jurnal Sains Kesihatan Malaysia, 1. pp. 1-7. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal.html
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Hashim, Rosnani Abdul Razak, Tariq Hashim, Suhaimi Kesan in vitro rilmenidine ke atas rembesan insulin
description	This study was carried out to determine the in vitro effect of a new antihypertensive drug, Rilmenidine, on insulin secretion. The direct effect of Rilmenidine on glucose-induced insulin secretion was studied using isolated rat pancreas. The concentrations of Rilmenidine used were based on the peak plasma concentration achieved with an oral dose of 1 mg. T a low concentration, Rilmenidine (0.35 ng/ml) significantly stimulated insulin secretion (p‹0.01). However, Rilmenidine showed a significantly weak inhibition (p< 0.05) at 3.5 ng/ml and a strong inhibitin at a higher concentration (35.0 ng/ml). The result showed that Rilmenidine exhibited significant stimulating and inhibitory effects on insulin secretion from the pancreas at different concentrations.
format	Article
author	Hashim, Rosnani Abdul Razak, Tariq Hashim, Suhaimi
author_facet	Hashim, Rosnani Abdul Razak, Tariq Hashim, Suhaimi
author_sort	Hashim, Rosnani
title	Kesan in vitro rilmenidine ke atas rembesan insulin
title_short	Kesan in vitro rilmenidine ke atas rembesan insulin
title_full	Kesan in vitro rilmenidine ke atas rembesan insulin
title_fullStr	Kesan in vitro rilmenidine ke atas rembesan insulin
title_full_unstemmed	Kesan in vitro rilmenidine ke atas rembesan insulin
title_sort	kesan in vitro rilmenidine ke atas rembesan insulin
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2003
url	http://irep.iium.edu.my/400/ http://irep.iium.edu.my/400/ http://irep.iium.edu.my/400/1/Jurnal_Sains_Kesihatan_Malaysia_Jilid_I_2003.pdf
first_indexed	2023-09-18T20:07:31Z
last_indexed	2023-09-18T20:07:31Z
_version_	1777407257455099904

Kesan in vitro rilmenidine ke atas rembesan insulin

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