Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler

Purpose: To determine the impact of healthy aging upon total retinal blood flow as derived by Spectral-Domain, Optical Coherence Tomography Doppler SD-OCT. Methods: SD-OCT Doppler blood flow was non-invasively measured using the RTVue system (Optovue Inc., USA). One eye of each of 6 healthy young (...

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Main Authors:	Yusof @ Alias, Firdaus, Tayyari, Faryan, Flanagan, John G, Hudson, Christopher
Format:	Conference or Workshop Item
Language:	English
Published:	2012
Subjects:	QC Physics RE Ophthalmology
Online Access:	http://irep.iium.edu.my/40365/ http://irep.iium.edu.my/40365/ http://irep.iium.edu.my/40365/1/Binder1.pdf

id	iium-40365
recordtype	eprints
spelling	iium-403652015-03-04T02:12:45Z http://irep.iium.edu.my/40365/ Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler Yusof @ Alias, Firdaus Tayyari, Faryan Flanagan, John G Hudson, Christopher QC Physics RE Ophthalmology Purpose: To determine the impact of healthy aging upon total retinal blood flow as derived by Spectral-Domain, Optical Coherence Tomography Doppler SD-OCT. Methods: SD-OCT Doppler blood flow was non-invasively measured using the RTVue system (Optovue Inc., USA). One eye of each of 6 healthy young (mean age 25.7; SD 3.5 years) and 6 healthy elderly (mean age 63.5; SD 1.8 years) subjects was randomly selected for the study and dilated using Mydriacyl 1%. A double circular scanning pattern was employed. A minimum of six separate SD-OCT Doppler measurements (i.e. each separate measurement comprising a superior nasal pupil scan and an inferior nasal pupil scan) were acquired. Total retinal blood flow was calculated, using data from valid scans only, by summing flow from all detectable venules. Results: 117 of 170 images (68.82%) were determined to be valid using the DOCTORC software (Centre for Ophthalmic Optics and Lasers, CA,USA). Mean total retinal blood flow for the young group was 44.96±15.59μl/min, while for the elderly group it was 39.45±13.20 μl/min. Two-sided t-test showed no significant difference between both groups (p=0.52). Linear regression analysis showed no significant correlation between total retinal blood flow and age (r=-0.31, p=0.33). Conclusions: Preliminary data acquired using SD-OCT Doppler shows no significant difference in retinal blood flow between a young and elderly group. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/40365/1/Binder1.pdf Yusof @ Alias, Firdaus and Tayyari, Faryan and Flanagan, John G and Hudson, Christopher (2012) Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler. In: ARVO 2012 Annual Meeting, 10 May 2012, Fort Lauderdale, FL, USA. http://www.arvo.org/Annual_Meeting/2012/Program/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QC Physics RE Ophthalmology
spellingShingle	QC Physics RE Ophthalmology Yusof @ Alias, Firdaus Tayyari, Faryan Flanagan, John G Hudson, Christopher Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
description	Purpose: To determine the impact of healthy aging upon total retinal blood flow as derived by Spectral-Domain, Optical Coherence Tomography Doppler SD-OCT. Methods: SD-OCT Doppler blood flow was non-invasively measured using the RTVue system (Optovue Inc., USA). One eye of each of 6 healthy young (mean age 25.7; SD 3.5 years) and 6 healthy elderly (mean age 63.5; SD 1.8 years) subjects was randomly selected for the study and dilated using Mydriacyl 1%. A double circular scanning pattern was employed. A minimum of six separate SD-OCT Doppler measurements (i.e. each separate measurement comprising a superior nasal pupil scan and an inferior nasal pupil scan) were acquired. Total retinal blood flow was calculated, using data from valid scans only, by summing flow from all detectable venules. Results: 117 of 170 images (68.82%) were determined to be valid using the DOCTORC software (Centre for Ophthalmic Optics and Lasers, CA,USA). Mean total retinal blood flow for the young group was 44.96±15.59μl/min, while for the elderly group it was 39.45±13.20 μl/min. Two-sided t-test showed no significant difference between both groups (p=0.52). Linear regression analysis showed no significant correlation between total retinal blood flow and age (r=-0.31, p=0.33). Conclusions: Preliminary data acquired using SD-OCT Doppler shows no significant difference in retinal blood flow between a young and elderly group.
format	Conference or Workshop Item
author	Yusof @ Alias, Firdaus Tayyari, Faryan Flanagan, John G Hudson, Christopher
author_facet	Yusof @ Alias, Firdaus Tayyari, Faryan Flanagan, John G Hudson, Christopher
author_sort	Yusof @ Alias, Firdaus
title	Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
title_short	Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
title_full	Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
title_fullStr	Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
title_full_unstemmed	Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
title_sort	age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler
publishDate	2012
url	http://irep.iium.edu.my/40365/ http://irep.iium.edu.my/40365/ http://irep.iium.edu.my/40365/1/Binder1.pdf
first_indexed	2023-09-18T20:57:54Z
last_indexed	2023-09-18T20:57:54Z
_version_	1777410427605483520

Age effects on retinal blood flow assessed using spectral-domain optical coherence tomography doppler

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