Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage

Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH). Methods:RBF measurements were obtained from 10 POAG with DH...

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Main Authors:	Hudson, Christopher, Espahbodi, Nadia, Shahidi, Ayda M, Yusof, Firdaus, Cheng, Richard, Jong, Monica, Graham, Trope, Buys, Yvonne M, Flanagan, John G
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	RE Ophthalmology
Online Access:	http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf http://irep.iium.edu.my/40376/4/ARVO_2014.pdf

id	iium-40376
recordtype	eprints
spelling	iium-403762014-12-30T01:53:04Z http://irep.iium.edu.my/40376/ Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G RE Ophthalmology Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH). Methods:RBF measurements were obtained from 10 POAG with DH (mean age 71.7, SD=7.39; 9 females)and 10 age matched POAG without DH (mean age 70, SD = 5.27; 6 females) using Doppler SD-OCT (RTVue; Optovue Inc, Fremont, CA, USA) as well as bi-directional laser Doppler flowmetry with densitometry (CLBF-100, Canon, Tokyo, Japan). TRBF measurements were compared between groups, within group for SRBF and IRBF, and for inter-ocular asymmetry (ANOVA; p<0.05). Correlation between TRBF and age, and TRBF and Mean Deviation of Humphrey automated perimetry were also analyzed. Results:Venous TRBF in the POAG with DH group (n=10, 27.1 μl/min, SD 7) was significantly lower than in the age-matched POAG without DH group (n=10, 38.83 μl/min, SD 10.66, p=0.009). RBF was not significantly different between the superior and inferior hemifields for either POAG with DH (p=0.763) or POAG without DH (p=0.481). In the POAG with DH group, venous TRBF was significantly lower in the DH eye (n=8, 28.73 μl/min, SD 6.87) compared to the contralateral eye without DH (n=8, 38.44 μl/min, SD 7.11, p=0.015). There was no significant difference between IOP, MD, BP, HR and MOPP between the POAG with and without DH groups. Also, there was no significant relationship between age or MD index of automated static perimetry with venous TRBF for the POAG with, and without DH group. Conclusions:Venous TRBF was significantly lower in the POAG with DH group compared to both the POAG without DH group and the contralateral eye of the POAG with DH group. There was no within eye asymmetry when comparing SRBF and IRBF either with or without DH, or when comparing the hemifield with DH to that without. 2014 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf application/pdf en http://irep.iium.edu.my/40376/4/ARVO_2014.pdf Hudson, Christopher and Espahbodi, Nadia and Shahidi, Ayda M and Yusof, Firdaus and Cheng, Richard and Jong, Monica and Graham, Trope and Buys, Yvonne M and Flanagan, John G (2014) Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage. In: ARVO Annual Meeting 2014, May 6th, 2014, Orlando, FL, USA. http://www.arvo.org/webs/am2014/abstract/sessions/320.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RE Ophthalmology
spellingShingle	RE Ophthalmology Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
description	Purpose:To investigate total retinal blood flow (TRBF) and retinal blood flow (RBF) in the superior (S) and the inferior (I) retinal hemifields in patients with primary open angle glaucoma (POAG) both with and without disc hemorrhage (DH). Methods:RBF measurements were obtained from 10 POAG with DH (mean age 71.7, SD=7.39; 9 females)and 10 age matched POAG without DH (mean age 70, SD = 5.27; 6 females) using Doppler SD-OCT (RTVue; Optovue Inc, Fremont, CA, USA) as well as bi-directional laser Doppler flowmetry with densitometry (CLBF-100, Canon, Tokyo, Japan). TRBF measurements were compared between groups, within group for SRBF and IRBF, and for inter-ocular asymmetry (ANOVA; p<0.05). Correlation between TRBF and age, and TRBF and Mean Deviation of Humphrey automated perimetry were also analyzed. Results:Venous TRBF in the POAG with DH group (n=10, 27.1 μl/min, SD 7) was significantly lower than in the age-matched POAG without DH group (n=10, 38.83 μl/min, SD 10.66, p=0.009). RBF was not significantly different between the superior and inferior hemifields for either POAG with DH (p=0.763) or POAG without DH (p=0.481). In the POAG with DH group, venous TRBF was significantly lower in the DH eye (n=8, 28.73 μl/min, SD 6.87) compared to the contralateral eye without DH (n=8, 38.44 μl/min, SD 7.11, p=0.015). There was no significant difference between IOP, MD, BP, HR and MOPP between the POAG with and without DH groups. Also, there was no significant relationship between age or MD index of automated static perimetry with venous TRBF for the POAG with, and without DH group. Conclusions:Venous TRBF was significantly lower in the POAG with DH group compared to both the POAG without DH group and the contralateral eye of the POAG with DH group. There was no within eye asymmetry when comparing SRBF and IRBF either with or without DH, or when comparing the hemifield with DH to that without.
format	Conference or Workshop Item
author	Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G
author_facet	Hudson, Christopher Espahbodi, Nadia Shahidi, Ayda M Yusof, Firdaus Cheng, Richard Jong, Monica Graham, Trope Buys, Yvonne M Flanagan, John G
author_sort	Hudson, Christopher
title	Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
title_short	Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
title_full	Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
title_fullStr	Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
title_full_unstemmed	Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
title_sort	retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage
publishDate	2014
url	http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/ http://irep.iium.edu.my/40376/1/Abstract_Nadia_FYA_ARVO_2014.pdf http://irep.iium.edu.my/40376/4/ARVO_2014.pdf
first_indexed	2023-09-18T20:57:55Z
last_indexed	2023-09-18T20:57:55Z
_version_	1777410428627845120

Retinal blood flow in patients with primary open angle glaucoma and optic disc hemorrhage

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