Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma

Background Traditionally, radical or modified radical neck dissection was performed as salvage procedure in persistent or recurrent neck disease after primary radiotherapy. This relatively radical procedure has produced lots of morbidity to the survivors. Objective To assess the feasibility...

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Main Authors:	Abdullah, Kahairi, I, Bing Tan, van den Brekel, Michiel, M, Baris Karakullukcu
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	RF Otorhinolaryngology
Online Access:	http://irep.iium.edu.my/40833/ http://irep.iium.edu.my/40833/ http://irep.iium.edu.my/40833/1/Binder1.pdf

id	iium-40833
recordtype	eprints
spelling	iium-408332015-03-05T01:55:56Z http://irep.iium.edu.my/40833/ Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma Abdullah, Kahairi I, Bing Tan van den Brekel, Michiel M, Baris Karakullukcu RF Otorhinolaryngology Background Traditionally, radical or modified radical neck dissection was performed as salvage procedure in persistent or recurrent neck disease after primary radiotherapy. This relatively radical procedure has produced lots of morbidity to the survivors. Objective To assess the feasibility of selective or superselective neck dissection as used after primary radiotherapy Methods Retrospective cohort analyses of patients treated in the Netherland Cancer Institute –Antony van Leeuwenhoek (NKI-AVL) from 1995 until 2012. All patients with squamous cell carcinoma of oropharynx, hypopharynx and larynx who received primary radiotherapy and underwent salvage neck dissection were included. Results A total of 27 patients with 29 neck dissections were included. Microscopically, viable pathological lymph nodes were found in 59% (n=17) of the neck dissection specimens. In 10 of the 17 specimens the tumor positive level corresponded to the pre-treatment involved neck level. Single level of pathological lymph node involvement were found in 65% (n=11) of the specimens and 73% (n=8) of these were involved level II. In only 6% (n=1) that the pathological lymph node involved level I and level V. level IV was involved in 18% (n=3) of the neck dissection specimens and in the remaining 76% (n=13), the pathological lymph node confined to the level II and III. Conclusion In carefully selected cases, selective neck dissection (level II,III,IV) is safe to perform as salvage procedure in persistent or recurrent neck disease following primary radiotherapy for squamous cell carcinoma of the pharynx and larynx. 2014 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/40833/1/Binder1.pdf Abdullah, Kahairi and I, Bing Tan and van den Brekel, Michiel and M, Baris Karakullukcu (2014) Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma. In: 6th Asia Pacific Otology, Neurotology & Skull Base Conference, 5th Asean Academy of Neuro-Otology & Audiology (AANOA) Congress & Asean Rhinology Forum , 29th-31st May 2014, Penang, Malaysia. (Unpublished) http://www.asiapacificorl2014.com/files/AsiaPacificORL2014_AbstractBook.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RF Otorhinolaryngology
spellingShingle	RF Otorhinolaryngology Abdullah, Kahairi I, Bing Tan van den Brekel, Michiel M, Baris Karakullukcu Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
description	Background Traditionally, radical or modified radical neck dissection was performed as salvage procedure in persistent or recurrent neck disease after primary radiotherapy. This relatively radical procedure has produced lots of morbidity to the survivors. Objective To assess the feasibility of selective or superselective neck dissection as used after primary radiotherapy Methods Retrospective cohort analyses of patients treated in the Netherland Cancer Institute –Antony van Leeuwenhoek (NKI-AVL) from 1995 until 2012. All patients with squamous cell carcinoma of oropharynx, hypopharynx and larynx who received primary radiotherapy and underwent salvage neck dissection were included. Results A total of 27 patients with 29 neck dissections were included. Microscopically, viable pathological lymph nodes were found in 59% (n=17) of the neck dissection specimens. In 10 of the 17 specimens the tumor positive level corresponded to the pre-treatment involved neck level. Single level of pathological lymph node involvement were found in 65% (n=11) of the specimens and 73% (n=8) of these were involved level II. In only 6% (n=1) that the pathological lymph node involved level I and level V. level IV was involved in 18% (n=3) of the neck dissection specimens and in the remaining 76% (n=13), the pathological lymph node confined to the level II and III. Conclusion In carefully selected cases, selective neck dissection (level II,III,IV) is safe to perform as salvage procedure in persistent or recurrent neck disease following primary radiotherapy for squamous cell carcinoma of the pharynx and larynx.
format	Conference or Workshop Item
author	Abdullah, Kahairi I, Bing Tan van den Brekel, Michiel M, Baris Karakullukcu
author_facet	Abdullah, Kahairi I, Bing Tan van den Brekel, Michiel M, Baris Karakullukcu
author_sort	Abdullah, Kahairi
title	Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
title_short	Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
title_full	Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
title_fullStr	Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
title_full_unstemmed	Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
title_sort	feasibility of selective salvage neck dissection (level ii, iii, iv) after primary radiotherapy of pharynx and larynx squamous cell carcinoma
publishDate	2014
url	http://irep.iium.edu.my/40833/ http://irep.iium.edu.my/40833/ http://irep.iium.edu.my/40833/1/Binder1.pdf
first_indexed	2023-09-18T20:58:32Z
last_indexed	2023-09-18T20:58:32Z
_version_	1777410467125264384

Feasibility of selective salvage neck dissection (level II, III, IV) after primary radiotherapy of pharynx and larynx squamous cell carcinoma

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