Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome

Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome

Purpose Acute Kidney Injury (AKI) is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. We aim to assess its incidence utilising both urine output and creatinine criteria, and its association with risk factors and outcome....

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Main Authors: Md Ralib, Azrina, Mat Nor, Mohd Basri
Format: Article
Language:English
Published: World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM) 2015
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/9/EPI_AKI_PaperJCC.pdf
id iium-41224
recordtype eprints
spelling iium-412242017-04-06T08:14:35Z http://irep.iium.edu.my/41224/ Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome Md Ralib, Azrina Mat Nor, Mohd Basri R Medicine (General) Purpose Acute Kidney Injury (AKI) is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. We aim to assess its incidence utilising both urine output and creatinine criteria, and its association with risk factors and outcome. Material and Methods This was a single centre, prospective observational study. All ICU patients more than 18 years were screened for inclusion in the study. Admission of less than 48 hours, post-elective surgery and ICU readmission were excluded. Results A total of 143 patients were recruited, of these, 65% had AKI, of which 18 (19%) were Stage 1, 23 (25%) Stage 2 and 52 (56%) Stage 3. Independent risk factors for AKI includes high APACHE II score and septic shock (OR of 1.20 (1.09 to 1.33) and 8.41 (1.49 to 47.6), respectively). 38% were classified as AKICr, and 61% as AKIuo, and in 34%, both AKICr and AKIuo were present. AKI was an independent risk factor for mortality (HR 2.61 (1.06 to 6.42)). Conclusions AKI is common in our ICU, and almost half are highest severity stage. Patients with high severity of illness and septic shock were at risk for AKI. The presence of AKI independently predicted mortality. World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM) 2015-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/41224/9/EPI_AKI_PaperJCC.pdf Md Ralib, Azrina and Mat Nor, Mohd Basri (2015) Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome. Journal of Critical Care, 30 (3). pp. 636-642. ISSN 0883-9441 http://www.journals.elsevier.com/journal-of-critical-care/ 10.1016/j.jcrc.2015.01.018
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Md Ralib, Azrina
Mat Nor, Mohd Basri
Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
description Purpose Acute Kidney Injury (AKI) is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. We aim to assess its incidence utilising both urine output and creatinine criteria, and its association with risk factors and outcome. Material and Methods This was a single centre, prospective observational study. All ICU patients more than 18 years were screened for inclusion in the study. Admission of less than 48 hours, post-elective surgery and ICU readmission were excluded. Results A total of 143 patients were recruited, of these, 65% had AKI, of which 18 (19%) were Stage 1, 23 (25%) Stage 2 and 52 (56%) Stage 3. Independent risk factors for AKI includes high APACHE II score and septic shock (OR of 1.20 (1.09 to 1.33) and 8.41 (1.49 to 47.6), respectively). 38% were classified as AKICr, and 61% as AKIuo, and in 34%, both AKICr and AKIuo were present. AKI was an independent risk factor for mortality (HR 2.61 (1.06 to 6.42)). Conclusions AKI is common in our ICU, and almost half are highest severity stage. Patients with high severity of illness and septic shock were at risk for AKI. The presence of AKI independently predicted mortality.
format Article
author Md Ralib, Azrina
Mat Nor, Mohd Basri
author_facet Md Ralib, Azrina
Mat Nor, Mohd Basri
author_sort Md Ralib, Azrina
title Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
title_short Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
title_full Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
title_fullStr Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
title_full_unstemmed Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome
title_sort acute kidney injury in a malaysian intensive care unit: assessment of incidence, risk factors and outcome
publisher World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM)
publishDate 2015
url http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/
http://irep.iium.edu.my/41224/9/EPI_AKI_PaperJCC.pdf
first_indexed 2023-09-18T20:59:03Z
last_indexed 2023-09-18T20:59:03Z
_version_ 1777410499953033216

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